Abstract
Sarcoidosis is a systemic inflammatory disease characterized by granuloma formation in affected organs and caused by dysregulated immune response to an unknown antigen. Sarcoidosis patients receiving immunosuppressive medications are at increased risk of infection. Lymphopenia is also commonly seen among patient with sarcoidosis. In this review, risk of infections, including opportunistic infections, will be outlined. Recommendations for vaccinations and prophylactic therapy based on literature review will also be summarized.
Original language | English |
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Pages (from-to) | 87-98 |
Number of pages | 12 |
Journal | Sarcoidosis Vasculitis and Diffuse Lung Diseases |
Volume | 37 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1 Jan 2020 |
Keywords
- sarcoidosis
- infections
- opportunistic infections
- vaccinations
- immunizations
- prophylaxis
- travel
- progressive multifocal leukoencephalopathy
- immunoglobulin replacement therapy
- secondary antibody deficiency
- long-term safety
- rheumatoid-arthritis
- herpes-zoster
- serious infections
- fungal-infections
- 1st manifestation
- united-states
- RHEUMATOID-ARTHRITIS
- SECONDARY ANTIBODY DEFICIENCY
- HERPES-ZOSTER
- SERIOUS INFECTIONS
- UNITED-STATES
- Sarcoidosis
- FUNGAL-INFECTIONS
- 1ST MANIFESTATION
- PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY
- IMMUNOGLOBULIN REPLACEMENT THERAPY
- LONG-TERM SAFETY