Induction of apoptosis in Ogg1-null mouse embryonic fibroblasts by GSH depletion is independent of DNA damage

Ellen B. Higgs, Roger Godschalk, Nicholas J. Coltman, Grant S. Stewart, Frederik-Jan van Schooten, Nikolas J. Hodges*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)27-35
Number of pages9
JournalToxicology Letters
Volume332
DOIs
Publication statusPublished - 10 Oct 2020

Keywords

  • Oxidative stress
  • 8-oxoguanine DNA glycosylase
  • 8-oxoG
  • Glutathione
  • Apoptosis
  • BASE-EXCISION-REPAIR
  • BUTHIONINE SULFOXIMINE
  • GLUTATHIONE DEPLETION
  • OXIDATIVE STRESS
  • ROS GENERATION
  • HEPG2 CELLS
  • ACCUMULATION
  • GENE
  • 8-HYDROXYGUANINE
  • MICE

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