Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients

Christian Nicolaj Andreassen*, Barry S. Rosenstein, Sarah L. Kerns, Harry Ostrer, Dirk De Ruysscher, Jamie A. Cesaretti, Gillian C. Barnett, Alison M. Dunning, Leila Dorling, Catharine M. L. West, Neil G. Burnet, Rebecca Elliott, Charlotte Coles, Emma Hall, Laura Fachal, Ana Vega, Antonio Gomez-Caamano, Christopher J. Talbot, R. Paul Symonds, Kim De RuyckHubert Thierens, Piet Ost, Jenny Chang-Claude, Petra Seibold, Odilia Popanda, Marie Overgaard, David Dearnaley, Matthew R. Sydes, David Azria, Christine Anne Koch, Matthew Parliament, Michael Blackshaw, Michael Sia, Maria J. Fuentes-Raspall, Teresa Ramon y Cajal, Agustin Barnadas, Danny Vesprini, Sara Gutierrez-Enriquez, Meritxell Molla, Orland Diez, John R. Yarnold, Jens Overgaard, Soren M. Bentzen, Jan Alsner

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)431-439
JournalRadiotherapy and Oncology
Issue number3
Publication statusPublished - Dec 2016


  • Normal tissue toxicity
  • Radiosensitivity
  • Ataxia telangiectasia mutated
  • p.Asp1853Asn
  • c.5557G > A

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