Increased risk for cancer after stroke at a young age: etiological relevance or incidental finding?

Christian Tanislav; Charles Christian Adarkwah; Louis Jakob; Karel Kostev

doi:10.1007/s00432-019-03022-x

Increased risk for cancer after stroke at a young age: etiological relevance or incidental finding?

Christian Tanislav^*, Charles Christian Adarkwah, Louis Jakob, Karel Kostev

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background Etiological factors, such as a malignant disease, in young stroke patients are often neglected. Therefore, in this study, we aimed to investigate the risk of developing cancer in young stroke survivors.

Methods The current case-control study sample included patients who received an initial ischemic stroke diagnosis documented in the Disease Analyzer database (IQVIA), which compiles data such as risk factors, drug prescriptions, and diagnoses obtained from general practitioners and specialists.

Results The stroke and non-stroke groups included 18,668 patients each; each group had 2836 (15.3%) participants 55 years (17.3% versus 9.5% and 29.4% versus 24.9%, respectively). The calculated hazard ratio for developing cancer within 10 years of follow-up was higher in the younger stroke population (

Conclusion In our cohort, young individuals aged

Original language	English
Pages (from-to)	3047-3054
Number of pages	8
Journal	Journal of Cancer Research and Clinical Oncology
Volume	145
Issue number	12
DOIs	https://doi.org/10.1007/s00432-019-03022-x
Publication status	Published - Dec 2019

Keywords

Young stroke
Cancer
Stroke etiology
ACUTE ISCHEMIC-STROKE
VENOUS THROMBOEMBOLISM
OCCULT CANCER
DISEASE
MULTICENTER
ADULTS
STATE

Access to Document

10.1007/s00432-019-03022-x

Cite this

@article{96f71d690e0246c493127dea6ef7fc08,

title = "Increased risk for cancer after stroke at a young age: etiological relevance or incidental finding?",

abstract = "Background Etiological factors, such as a malignant disease, in young stroke patients are often neglected. Therefore, in this study, we aimed to investigate the risk of developing cancer in young stroke survivors.Methods The current case-control study sample included patients who received an initial ischemic stroke diagnosis documented in the Disease Analyzer database (IQVIA), which compiles data such as risk factors, drug prescriptions, and diagnoses obtained from general practitioners and specialists.Results The stroke and non-stroke groups included 18,668 patients each; each group had 2836 (15.3%) participants 55 years (17.3% versus 9.5% and 29.4% versus 24.9%, respectively). The calculated hazard ratio for developing cancer within 10 years of follow-up was higher in the younger stroke population (Conclusion In our cohort, young individuals aged",

keywords = "Young stroke, Cancer, Stroke etiology, ACUTE ISCHEMIC-STROKE, VENOUS THROMBOEMBOLISM, OCCULT CANCER, DISEASE, MULTICENTER, ADULTS, STATE",

author = "Christian Tanislav and Adarkwah, {Charles Christian} and Louis Jakob and Karel Kostev",

note = "Publisher Copyright: {\textcopyright} 2019, Springer-Verlag GmbH Germany, part of Springer Nature.",

year = "2019",

month = dec,

doi = "10.1007/s00432-019-03022-x",

language = "English",

volume = "145",

pages = "3047--3054",

journal = "Journal of Cancer Research and Clinical Oncology",

issn = "0171-5216",

publisher = "Springer, Cham",

number = "12",

}

TY - JOUR

T1 - Increased risk for cancer after stroke at a young age

T2 - etiological relevance or incidental finding?

AU - Tanislav, Christian

AU - Adarkwah, Charles Christian

AU - Jakob, Louis

AU - Kostev, Karel

PY - 2019/12

Y1 - 2019/12

N2 - Background Etiological factors, such as a malignant disease, in young stroke patients are often neglected. Therefore, in this study, we aimed to investigate the risk of developing cancer in young stroke survivors.Methods The current case-control study sample included patients who received an initial ischemic stroke diagnosis documented in the Disease Analyzer database (IQVIA), which compiles data such as risk factors, drug prescriptions, and diagnoses obtained from general practitioners and specialists.Results The stroke and non-stroke groups included 18,668 patients each; each group had 2836 (15.3%) participants 55 years (17.3% versus 9.5% and 29.4% versus 24.9%, respectively). The calculated hazard ratio for developing cancer within 10 years of follow-up was higher in the younger stroke population (Conclusion In our cohort, young individuals aged

AB - Background Etiological factors, such as a malignant disease, in young stroke patients are often neglected. Therefore, in this study, we aimed to investigate the risk of developing cancer in young stroke survivors.Methods The current case-control study sample included patients who received an initial ischemic stroke diagnosis documented in the Disease Analyzer database (IQVIA), which compiles data such as risk factors, drug prescriptions, and diagnoses obtained from general practitioners and specialists.Results The stroke and non-stroke groups included 18,668 patients each; each group had 2836 (15.3%) participants 55 years (17.3% versus 9.5% and 29.4% versus 24.9%, respectively). The calculated hazard ratio for developing cancer within 10 years of follow-up was higher in the younger stroke population (Conclusion In our cohort, young individuals aged

KW - Young stroke

KW - Cancer

KW - Stroke etiology

KW - ACUTE ISCHEMIC-STROKE

KW - VENOUS THROMBOEMBOLISM

KW - OCCULT CANCER

KW - DISEASE

KW - MULTICENTER

KW - ADULTS

KW - STATE

U2 - 10.1007/s00432-019-03022-x

DO - 10.1007/s00432-019-03022-x

M3 - Article

SN - 0171-5216

VL - 145

SP - 3047

EP - 3054

JO - Journal of Cancer Research and Clinical Oncology

JF - Journal of Cancer Research and Clinical Oncology

IS - 12

ER -