Increased Myogenic and Protein Turnover Signaling in Skeletal Muscle of Chronic Obstructive Pulmonary Disease Patients With Sarcopenia

Anita E. M. Kneppers, Ramon C. J. Langen, Harry R. Gosker, Lex B. Verdijk, Nanca Cebron Lipovec, Pieter A. Leermakers, Marco C. J. M. Kelders, Chiel C. de Theije, Daniel Omersa, Mitja Lainscak, Annemie M. W. J. Schols*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Original languageEnglish
Pages (from-to)637.e1-637.e11
Number of pages11
JournalJournal of the American Medical Directors Association
Volume18
Issue number7
DOIs
Publication statusPublished - 1 Jul 2017

Keywords

  • Muscular atrophy
  • protein biosynthesis
  • proteolysis
  • myogenic differentiation
  • MYOBLAST DIFFERENTIATION
  • NUTRITIONAL DEPLETION
  • ECCENTRIC EXERCISE
  • OXIDATIVE STRESS
  • SATELLITE CELLS
  • MODERATE COPD
  • QUADRICEPS
  • AUTOPHAGY
  • EXPRESSION
  • ATROPHY

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