Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transport chain

Jian Jiang, Jacob J. Briede, Danyel G. J. Jennen, Anke Van Summeren, Karen Saritas-Brauers, Gert Schaart, Jos C. S. Kleinjans, Theo M. C. M. de Kok

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)
Original languageEnglish
Pages (from-to)139-150
JournalToxicology Letters
Issue number2
Publication statusPublished - 16 Apr 2015


  • Toxicogenomics
  • Acetaminophen
  • HepG2
  • Microarray
  • ESR
  • Mitochondrial ROS

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