Increased cardiovascular risk in patients with rheumatoid arthritis: an overview

D. Puttevils; P. de Vusser; P. Geusens; J. Dens

doi:10.1080/AC.69.2.3017291

Increased cardiovascular risk in patients with rheumatoid arthritis: an overview

D. Puttevils^*, P. de Vusser, P. Geusens, J. Dens

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Patients with established rheumatoid arthritis (RA) have a higher cardiovascular morbidity and mortality in comparison with the general population. It is considered to be an independent risk factor for cardiovascular disease. The purpose of this article is to describe the mechanisms responsible for accelerated atherogenesis in RA patients and to give an overview of the effects of different RA therapies (methotrexate, TNF antagonists and other biologicals).

Original language	English
Pages (from-to)	111-118
Number of pages	8
Journal	Acta Cardiologica
Volume	69
Issue number	2
DOIs	https://doi.org/10.1080/AC.69.2.3017291
Publication status	Published - Apr 2014

Keywords

Cardiovascular risk
atherogenesis
rheumatoid arthritis
TNF antagonists
heart failure
NECROSIS-FACTOR-ALPHA
CONGESTIVE-HEART-FAILURE
C-REACTIVE PROTEIN
IMPROVES ENDOTHELIAL FUNCTION
CAUSE-SPECIFIC MORTALITY
CORONARY-ARTERY-DISEASE
LONG-TERM TREATMENT
ANTI-TNF THERAPY
INSULIN-RESISTANCE
INFLAMMATORY POLYARTHRITIS

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10.1080/AC.69.2.3017291

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title = "Increased cardiovascular risk in patients with rheumatoid arthritis: an overview",

abstract = "Patients with established rheumatoid arthritis (RA) have a higher cardiovascular morbidity and mortality in comparison with the general population. It is considered to be an independent risk factor for cardiovascular disease. The purpose of this article is to describe the mechanisms responsible for accelerated atherogenesis in RA patients and to give an overview of the effects of different RA therapies (methotrexate, TNF antagonists and other biologicals).",

keywords = "Cardiovascular risk, atherogenesis, rheumatoid arthritis, TNF antagonists, heart failure, NECROSIS-FACTOR-ALPHA, CONGESTIVE-HEART-FAILURE, C-REACTIVE PROTEIN, IMPROVES ENDOTHELIAL FUNCTION, CAUSE-SPECIFIC MORTALITY, CORONARY-ARTERY-DISEASE, LONG-TERM TREATMENT, ANTI-TNF THERAPY, INSULIN-RESISTANCE, INFLAMMATORY POLYARTHRITIS",

author = "D. Puttevils and {de Vusser}, P. and P. Geusens and J. Dens",

year = "2014",

month = apr,

doi = "10.1080/AC.69.2.3017291",

language = "English",

volume = "69",

pages = "111--118",

journal = "Acta Cardiologica",

issn = "0001-5385",

publisher = "Routledge/Taylor & Francis Group",

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TY - JOUR

T1 - Increased cardiovascular risk in patients with rheumatoid arthritis: an overview

AU - Puttevils, D.

AU - de Vusser, P.

AU - Geusens, P.

AU - Dens, J.

PY - 2014/4

Y1 - 2014/4

N2 - Patients with established rheumatoid arthritis (RA) have a higher cardiovascular morbidity and mortality in comparison with the general population. It is considered to be an independent risk factor for cardiovascular disease. The purpose of this article is to describe the mechanisms responsible for accelerated atherogenesis in RA patients and to give an overview of the effects of different RA therapies (methotrexate, TNF antagonists and other biologicals).

AB - Patients with established rheumatoid arthritis (RA) have a higher cardiovascular morbidity and mortality in comparison with the general population. It is considered to be an independent risk factor for cardiovascular disease. The purpose of this article is to describe the mechanisms responsible for accelerated atherogenesis in RA patients and to give an overview of the effects of different RA therapies (methotrexate, TNF antagonists and other biologicals).

KW - Cardiovascular risk

KW - atherogenesis

KW - rheumatoid arthritis

KW - TNF antagonists

KW - heart failure

KW - NECROSIS-FACTOR-ALPHA

KW - CONGESTIVE-HEART-FAILURE

KW - C-REACTIVE PROTEIN

KW - IMPROVES ENDOTHELIAL FUNCTION

KW - CAUSE-SPECIFIC MORTALITY

KW - CORONARY-ARTERY-DISEASE

KW - LONG-TERM TREATMENT

KW - ANTI-TNF THERAPY

KW - INSULIN-RESISTANCE

KW - INFLAMMATORY POLYARTHRITIS

U2 - 10.1080/AC.69.2.3017291

DO - 10.1080/AC.69.2.3017291

M3 - Article

SN - 0001-5385

VL - 69

SP - 111

EP - 118

JO - Acta Cardiologica

JF - Acta Cardiologica

IS - 2

ER -

Increased cardiovascular risk in patients with rheumatoid arthritis: an overview

Abstract

Keywords

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