Increased cardiovascular risk in patients with rheumatoid arthritis: an overview

D. Puttevils, P. de Vusser, P. Geusens, J. Dens

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Patients with established rheumatoid arthritis (RA) have a higher cardiovascular morbidity and mortality in comparison with the general population. It is considered to be an independent risk factor for cardiovascular disease. The purpose of this article is to describe the mechanisms responsible for accelerated atherogenesis in RA patients and to give an overview of the effects of different RA therapies (methotrexate, TNF antagonists and other biologicals).

Original languageEnglish
Pages (from-to)111-118
Number of pages8
JournalActa Cardiologica
Volume69
Issue number2
DOIs
Publication statusPublished - Apr 2014

Keywords

  • Cardiovascular risk
  • atherogenesis
  • rheumatoid arthritis
  • TNF antagonists
  • heart failure
  • NECROSIS-FACTOR-ALPHA
  • CONGESTIVE-HEART-FAILURE
  • C-REACTIVE PROTEIN
  • IMPROVES ENDOTHELIAL FUNCTION
  • CAUSE-SPECIFIC MORTALITY
  • CORONARY-ARTERY-DISEASE
  • LONG-TERM TREATMENT
  • ANTI-TNF THERAPY
  • INSULIN-RESISTANCE
  • INFLAMMATORY POLYARTHRITIS

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