Increase in tacrolimus exposure after steroid tapering is influenced by CYP3A5 and pregnane X receptor genetic polymorphisms in renal transplant recipients

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1668-1675
Number of pages9
JournalNephrology Dialysis Transplantation
Volume33
Issue number9
DOIs
Publication statusPublished - 1 Sep 2018

Keywords

  • pharmacokinetics
  • pharmacogenetics
  • pregnane X receptor (PXR)
  • tacrolimus
  • therapeutic drug monitoring
  • P-GLYCOPROTEIN
  • ORGAN-TRANSPLANTATION
  • HUMAN HEPATOCYTES
  • PHARMACOKINETICS
  • EXPRESSION
  • CORTICOSTEROIDS
  • DEXAMETHASONE
  • DISPOSITION
  • COMBINATION
  • METABOLISM

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