Incidence of Distinct Repetitive Atrial Activation Patterns as a Metric for Atrial Fibrillation Complexity

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Abstract

Highly complex and irregular atrial activation patterns during atrial fibrillation (AF) can occasionally be interrupted by repetitive atrial activation patterns (RAAPs). These patterns are thought to be generated by mechanisms that initiate or maintain AF episodes are therefore, might be more diverse in patients with more complex forms of AF We quantified RAAP diversity by the half decay time of the ratio of the unprecedented RAAPs to the total num{###} ber of RAAPs in a goat model with different durations of sustained AF[3 weeks (3wkAF, n=8) and 22 weeks (22wkAF, n=8)]. 32 recordings from left and right atria (LA/RA) of each goat were analyzed. 24 out of 32 curves could be modeled as exponential decay functions with adjusted R-squared > 0.75 while others presented more irregular decaying patterns (3wkAF LA:2 RA:3,22wkAF LA: 1 RA:2). Half decay rates were significantly shorter in LAs of 3wkAF goats (δ3wkAF=23.67s vs. δ22wkAF=32.86s,p < 0.05, Mann-Whitney U-test). There was no significant difference in RA.

Original languageEnglish
Title of host publication2022 Computing in Cardiology (CinC)
Number of pages4
Volume49
DOIs
Publication statusPublished - 2022

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