In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease

Joao Casaca-Carreira; Lodewijk J. A. Toonen; Melvin M. Evers; Ali Jahanshahi; Willeke M. C. van-Roon-Mom; Yasin Temel

doi:10.1016/j.biopha.2016.09.007

In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease

Joao Casaca-Carreira, Lodewijk J. A. Toonen, Melvin M. Evers, Ali Jahanshahi, Willeke M. C. van-Roon-Mom, Yasin Temel

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	93-96
Journal	Biomedicine & Pharmacotherapy
Volume	84
DOIs	https://doi.org/10.1016/j.biopha.2016.09.007
Publication status	Published - Dec 2016

Keywords

HD
Exon skipping
Mouse
Intracerebroventricular
RNA

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10.1016/j.biopha.2016.09.007

Cite this

Casaca-Carreira, J., Toonen, L. J. A., Evers, M. M., Jahanshahi, A., van-Roon-Mom, W. M. C., & Temel, Y. (2016). In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease. Biomedicine & Pharmacotherapy, 84, 93-96. https://doi.org/10.1016/j.biopha.2016.09.007

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title = "In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease",

keywords = "HD, Exon skipping, Mouse, Intracerebroventricular, RNA",

author = "Joao Casaca-Carreira and Toonen, {Lodewijk J. A.} and Evers, {Melvin M.} and Ali Jahanshahi and van-Roon-Mom, {Willeke M. C.} and Yasin Temel",

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In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease. / Casaca-Carreira, Joao; Toonen, Lodewijk J. A.; Evers, Melvin M.; Jahanshahi, Ali; van-Roon-Mom, Willeke M. C.; Temel, Yasin.

In: Biomedicine & Pharmacotherapy, Vol. 84, 12.2016, p. 93-96.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease

AU - Casaca-Carreira, Joao

AU - Toonen, Lodewijk J. A.

AU - Evers, Melvin M.

AU - Jahanshahi, Ali

AU - van-Roon-Mom, Willeke M. C.

AU - Temel, Yasin

PY - 2016/12

Y1 - 2016/12

KW - HD

KW - Exon skipping

KW - Mouse

KW - Intracerebroventricular

KW - RNA

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JF - Biomedicine & Pharmacotherapy

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