In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease

Joao Casaca-Carreira; Lodewijk J. A. Toonen; Melvin M. Evers; Ali Jahanshahi; Willeke M. C. van-Roon-Mom; Yasin Temel

doi:10.1016/j.biopha.2016.09.007

In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease

Joao Casaca-Carreira^*, Lodewijk J. A. Toonen, Melvin M. Evers, Ali Jahanshahi, Willeke M. C. van-Roon-Mom, Yasin Temel

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Web of Science)

Original language	English
Pages (from-to)	93-96
Journal	Biomedicine & Pharmacotherapy
Volume	84
DOIs	https://doi.org/10.1016/j.biopha.2016.09.007
Publication status	Published - Dec 2016

Keywords

HD
Exon skipping
Mouse
Intracerebroventricular
RNA

Access to Document

10.1016/j.biopha.2016.09.007

Cite this

@article{0bf074a427854e318d4cd4c4c4d58199,

title = "In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease",

keywords = "HD, Exon skipping, Mouse, Intracerebroventricular, RNA",

author = "Joao Casaca-Carreira and Toonen, {Lodewijk J. A.} and Evers, {Melvin M.} and Ali Jahanshahi and van-Roon-Mom, {Willeke M. C.} and Yasin Temel",

year = "2016",

month = dec,

doi = "10.1016/j.biopha.2016.09.007",

language = "English",

volume = "84",

pages = "93--96",

journal = "Biomedicine & Pharmacotherapy",

issn = "0753-3322",

publisher = "Elsevier Masson",

}

In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease. / Casaca-Carreira, Joao; Toonen, Lodewijk J. A.; Evers, Melvin M.; Jahanshahi, Ali; van-Roon-Mom, Willeke M. C.; Temel, Yasin.

In: Biomedicine & Pharmacotherapy, Vol. 84, 12.2016, p. 93-96.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington's disease

AU - Casaca-Carreira, Joao

AU - Toonen, Lodewijk J. A.

AU - Evers, Melvin M.

AU - Jahanshahi, Ali

AU - van-Roon-Mom, Willeke M. C.

AU - Temel, Yasin

PY - 2016/12

Y1 - 2016/12

KW - HD

KW - Exon skipping

KW - Mouse

KW - Intracerebroventricular

KW - RNA

U2 - 10.1016/j.biopha.2016.09.007

DO - 10.1016/j.biopha.2016.09.007

M3 - Article

C2 - 27639545

VL - 84

SP - 93

EP - 96

JO - Biomedicine & Pharmacotherapy

JF - Biomedicine & Pharmacotherapy

SN - 0753-3322

ER -