In vitro fertilization does not increase the incidence of de novo copy number alterations in fetal and placental lineages

Masoud Zamani Esteki*, Triin Viltrop, Olga Tsuiko, Airi Tiirats, Mariann Koel, Margit Noukas, Olga Zilina, Katre Teearu, Heidi Marjonen, Hanna Kahila, Jeroen Meekels, Viveca Soderstrom-Anttila, Anne-Maria Suikkari, Aila Tiitinen, Reedik Magi, Sulev Koks, Nina Kaminen-Ahola, Ants Kurg, Thierry Voet*, Joris Robert Vermeesch*Andres Salumets*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1699-1705
Number of pages6
JournalNature Medicine
Volume25
Issue number11
DOIs
Publication statusPublished - 4 Nov 2019

Keywords

  • HIDDEN-MARKOV MODEL
  • HUMAN-EMBRYOS
  • CHROMOSOME INSTABILITY
  • MOSAICISM
  • GENOME
  • ANEUPLOIDY
  • COMMON
  • ABNORMALITIES
  • CONSTITUTION
  • BLASTOCYSTS

Cite this

Esteki, M. Z., Viltrop, T., Tsuiko, O., Tiirats, A., Koel, M., Noukas, M., Zilina, O., Teearu, K., Marjonen, H., Kahila, H., Meekels, J., Soderstrom-Anttila, V., Suikkari, A-M., Tiitinen, A., Magi, R., Koks, S., Kaminen-Ahola, N., Kurg, A., Voet, T., ... Salumets, A. (2019). In vitro fertilization does not increase the incidence of de novo copy number alterations in fetal and placental lineages. Nature Medicine, 25(11), 1699-1705. https://doi.org/10.1038/s41591-019-0620-2