In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy

Shuo Zhang; Christian J. F. Bertens; Roel J. Erckens; Frank J. H. M. van den Biggelaar; Tos T. J. M. Berendschot; Carroll A. B. Webers; Rudy M. M. A. Nuijts; Marlies Gijs

doi:10.1016/j.dib.2019.104694

In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy

Shuo Zhang, Christian J. F. Bertens^*, Roel J. Erckens, Frank J. H. M. van den Biggelaar, Tos T. J. M. Berendschot, Carroll A. B. Webers, Rudy M. M. A. Nuijts, Marlies Gijs

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., "Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of topically applied ketorolac tromethamine in vitro and in vivo" (Bertens and Zhang, et al.). Detection of ketorolac tromethamine in pig eyes was performed in vitro and rabbit eyes in vivo. Extracted aqueous humor samples from pig and rabbit eyes were measured in vitro using a cuvette. This manuscript shows the spectral Raman data without pre-treatment or analysis from ocular tissues and provides further information towards aqueous humor research via alternative data processing methods. Furthermore, the raw data enclosed may be used for future aqueous humor investigations and pharmaceutical research. (C) 2019 The Authors. Published by Elsevier Inc.

Original language	English
Article number	104694
Number of pages	9
Journal	Data in brief
Volume	27
DOIs	https://doi.org/10.1016/j.dib.2019.104694
Publication status	Published - Dec 2019

Keywords

Raman spectroscopy
Ophthalmology
Ketorolac tromethamine
Rabbits
Aqueous humor
Pig eyes

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10.1016/j.dib.2019.104694Licence: CC BY

Cite this

@article{ac241868b3414a26b7a22ee4bb97a52d,

title = "In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy",

abstract = "This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., {"}Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of topically applied ketorolac tromethamine in vitro and in vivo{"} (Bertens and Zhang, et al.). Detection of ketorolac tromethamine in pig eyes was performed in vitro and rabbit eyes in vivo. Extracted aqueous humor samples from pig and rabbit eyes were measured in vitro using a cuvette. This manuscript shows the spectral Raman data without pre-treatment or analysis from ocular tissues and provides further information towards aqueous humor research via alternative data processing methods. Furthermore, the raw data enclosed may be used for future aqueous humor investigations and pharmaceutical research. (C) 2019 The Authors. Published by Elsevier Inc.",

keywords = "Raman spectroscopy, Ophthalmology, Ketorolac tromethamine, Rabbits, Aqueous humor, Pig eyes",

author = "Shuo Zhang and Bertens, {Christian J. F.} and Erckens, {Roel J.} and {van den Biggelaar}, {Frank J. H. M.} and Berendschot, {Tos T. J. M.} and Webers, {Carroll A. B.} and Nuijts, {Rudy M. M. A.} and Marlies Gijs",

note = "Funding Information: This research was performed under the framework of the Chemelot Institute for Science and Technology (InSciTe). Publisher Copyright: {\textcopyright} 2019 The Authors",

year = "2019",

month = dec,

doi = "10.1016/j.dib.2019.104694",

language = "English",

volume = "27",

journal = "Data in brief",

issn = "2352-3409",

publisher = "Elsevier Science",

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T1 - In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy

AU - Zhang, Shuo

AU - Bertens, Christian J. F.

AU - Erckens, Roel J.

AU - van den Biggelaar, Frank J. H. M.

AU - Berendschot, Tos T. J. M.

AU - Webers, Carroll A. B.

AU - Nuijts, Rudy M. M. A.

AU - Gijs, Marlies

PY - 2019/12

Y1 - 2019/12

N2 - This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., "Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of topically applied ketorolac tromethamine in vitro and in vivo" (Bertens and Zhang, et al.). Detection of ketorolac tromethamine in pig eyes was performed in vitro and rabbit eyes in vivo. Extracted aqueous humor samples from pig and rabbit eyes were measured in vitro using a cuvette. This manuscript shows the spectral Raman data without pre-treatment or analysis from ocular tissues and provides further information towards aqueous humor research via alternative data processing methods. Furthermore, the raw data enclosed may be used for future aqueous humor investigations and pharmaceutical research. (C) 2019 The Authors. Published by Elsevier Inc.

AB - This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., "Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of topically applied ketorolac tromethamine in vitro and in vivo" (Bertens and Zhang, et al.). Detection of ketorolac tromethamine in pig eyes was performed in vitro and rabbit eyes in vivo. Extracted aqueous humor samples from pig and rabbit eyes were measured in vitro using a cuvette. This manuscript shows the spectral Raman data without pre-treatment or analysis from ocular tissues and provides further information towards aqueous humor research via alternative data processing methods. Furthermore, the raw data enclosed may be used for future aqueous humor investigations and pharmaceutical research. (C) 2019 The Authors. Published by Elsevier Inc.

KW - Raman spectroscopy

KW - Ophthalmology

KW - Ketorolac tromethamine

KW - Rabbits

KW - Aqueous humor

KW - Pig eyes

U2 - 10.1016/j.dib.2019.104694

DO - 10.1016/j.dib.2019.104694

M3 - Article

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SN - 2352-3409

VL - 27

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