Improvement of Clostridium tumour targeting vectors evaluated in rat rhabdomyosarcomas

J Theys, W Landuyt, S Nuyts, L Van Mellaert, E Bosmans, A Rijnders, W Van den Bogaert, A van Oosterom, J Anne, P Lambin*

*Corresponding author for this work

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Abstract

Previous studies have demonstrated the feasibility of using apathogenic clostridia as a promising strategy for hypoxia-specific tumour targeting. The present study shows that the use of the vascular targeting compound combretastatin A-4 phosphate could significantly (P

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalFems Immunology and Medical Microbiology
Volume30
Issue number1
DOIs
Publication statusPublished - Feb 2001

Keywords

  • anti-cancer treatment
  • gene therapy
  • hypoxia
  • vascular targeting
  • Clostridium
  • COMBRETASTATIN A-4
  • VASCULATURE
  • PHOSPHATE
  • BACTERIA
  • THERAPY
  • ALPHA

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