Improved seizure control and regaining cognitive milestones after vagus nerve stimulation revision surgery in Lennox-Gastaut syndrome

Hilde M. Braakman*, Joke Creemers, Danny M. Hilkman, Sylvia Klinkenberg, Suzanne M. Koudijs, Mariette Debeij-van Hall, Erwin M. Cornips

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


We report a child with Lennox-Gastaut syndrome with an increase in seizure frequency and loss of psychomotor skills due to a disintegrated cervical VNS lead, not detected during standard device monitoring. The lead was completely removed and replaced by a new 303 lead on the same nerve segment. After reinitiating VNS, side effects forced us to switch it off, resulting in immediate seizure recurrence. EEG recording demonstrated a non-convulsive status epileptiais that was halted by reinitiating VNS therapy. Thereafter, he remained seizure free for eight months, and regained psychomotor development. (C) 2018 The Authors. Published by Elsevier Inc.

Original languageEnglish
Pages (from-to)111-113
Number of pages3
JournalEpilepsy & behavior case reports
Publication statusPublished - 2018


  • Lennox-Gastaut syndrome
  • Refractory epilepsy
  • Revision surgery
  • Seizure freedom
  • Vagus nerve stimulation

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