Impaired SMAD1/5 Mechanotransduction and Cx37 (Connexin37) Expression Enable Pathological Vessel Enlargement and Shunting

Keyphrases

• Smad1 100%
• Mechanotransduction 100%
• Shunt 100%
• Vessel Enlargement 100%
• Connexin 37 100%
• Shear Stress 40%
• BMP9 40%
• Arteriovenous Malformation 40%
• Tumor Necrosis Factor-α 20%
• Endothelial Cells 20%
• Compound Heterozygous mutation 20%
• Vascular Malformation 20%
• Yolk Sac 20%
• Specific Compounds 20%
• Enlargement 10%
• Vascular Remodeling 10%
• Expression Pattern 10%
• Capillary 10%
• Flow Condition 10%
• Mouse Embryo 10%
• Directional Migration 10%
• Mechanical Signals 10%
• Genetic Disease 10%
• Mechanosensitive 10%
• Endoglin 10%
• Direct Connection 10%
• Hereditary Hemorrhagic Telangiectasia 10%
• ALK1 10%
• Dorsal Aorta 10%
• Capillary Beds 10%

INIS

• vessels 100%
• malformations 100%
• shear 66%
• receptors 33%
• capillaries 33%
• genetics 33%
• embryos 33%
• tumor necrosis factor 33%
• yolk 33%
• data 16%
• stimulation 16%
• losses 16%
• mice 16%
• bones 16%
• proteins 16%
• migration 16%
• signals 16%
• kinases 16%
• connections 16%
• ligands 16%
• aorta 16%
• shunts 16%
• hereditary diseases 16%

Biochemistry, Genetics and Molecular Biology

• Shear Stress 100%
• Mechanotransduction 100%
• Tumor Necrosis Factor 50%
• Compound Heterozygosity 50%
• Genetics 25%
• Wild Type 25%
• Phosphotransferase 25%
• Kinase 25%
• Genetic Disorder 25%
• Bone Morphogenetic Protein 25%
• Activin Receptor 25%
• Endoglin 25%
• Dorsal Aorta 25%