TY - JOUR
T1 - Impact of weight loss and maintenance with ad libitum diets varying in protein and glycemic index content on metabolic syndrome
AU - Papadaki, A.
AU - Linardakis, M.
AU - Plada, M.
AU - Larsen, T.M.
AU - Damsgaard, C.T.
AU - van Baak, M.A.
AU - Jebb, S.
AU - Pfeiffer, A.F.
AU - Martinez, J.A.
AU - Handjieva Darlenska, T.
AU - Kunesova, M.
AU - Holst, C.
AU - Saris, W.H.
AU - Astrup, A.
AU - Kafatos, A.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - OBJECTIVES: We investigated the effects of weight loss and maintenance that varied with regard to protein content and glycemic index (GI) on syndrome (MetSyn) status. METHODS: Secondary analyses were performed Diet, Obesity and Genes (DiOGenes) study (2006-2008), a randomized dietary intervention. Nine hundred and thirty-eight overweight and obese from eight European countries entered an 8-wk low-calorie-diet period. hundred and seventy-three adults who lost at least 8% of their body randomized to one of five ad libitum diets for 6 mo: 1) low-protein (LGI); 2) LP/high-GI (HGI); 3) high-protein (HP)/LGI; 4) HP/HGI; and 5) diet. MetSyn prevalence and a standardized MetSyn score were assessed at baseline, after the low-calorie diet, and after the intervention. loss among participants while on the low-calorie diet significantly MetSyn prevalence (33.9% versus 15.9%; P < 0.001) and MetSyn score (- -4.45; P < 0.001). During weight maintenance, significant changes in were observed between the groups, with the highest increase detected in LP/HGI group (P = 0.039, partial eta2 = 0.023). Protein, GI, and their interaction did not have isolated effects on study outcomes. protein nor GI affected MetSyn status in this sample of European obese adults. However, a diet with a combination of an increased protein-to-carbohydrate ratio with low-GI foods had beneficial effects factors.
AB - OBJECTIVES: We investigated the effects of weight loss and maintenance that varied with regard to protein content and glycemic index (GI) on syndrome (MetSyn) status. METHODS: Secondary analyses were performed Diet, Obesity and Genes (DiOGenes) study (2006-2008), a randomized dietary intervention. Nine hundred and thirty-eight overweight and obese from eight European countries entered an 8-wk low-calorie-diet period. hundred and seventy-three adults who lost at least 8% of their body randomized to one of five ad libitum diets for 6 mo: 1) low-protein (LGI); 2) LP/high-GI (HGI); 3) high-protein (HP)/LGI; 4) HP/HGI; and 5) diet. MetSyn prevalence and a standardized MetSyn score were assessed at baseline, after the low-calorie diet, and after the intervention. loss among participants while on the low-calorie diet significantly MetSyn prevalence (33.9% versus 15.9%; P < 0.001) and MetSyn score (- -4.45; P < 0.001). During weight maintenance, significant changes in were observed between the groups, with the highest increase detected in LP/HGI group (P = 0.039, partial eta2 = 0.023). Protein, GI, and their interaction did not have isolated effects on study outcomes. protein nor GI affected MetSyn status in this sample of European obese adults. However, a diet with a combination of an increased protein-to-carbohydrate ratio with low-GI foods had beneficial effects factors.
U2 - 10.1016/j.nut.2013.09.001
DO - 10.1016/j.nut.2013.09.001
M3 - Article
SN - 0899-9007
VL - 30
SP - 410
EP - 417
JO - Nutrition
JF - Nutrition
IS - 4
ER -