Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03)

Avani Athauda; Matthew Nankivell; Ruth E. Langley; Derek Alderson; William Allum; Heike I. Grabsch; Naureen Starling; Ian Chau; David Cunningham

doi:10.1016/j.ejca.2020.06.005

Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03)

Avani Athauda, Matthew Nankivell, Ruth E. Langley, Derek Alderson, William Allum, Heike I. Grabsch, Naureen Starling, Ian Chau, David Cunningham^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	45-56
Number of pages	12
Journal	European Journal of Cancer
Volume	137
DOIs	https://doi.org/10.1016/j.ejca.2020.06.005
Publication status	Published - Sep 2020

Keywords

Age
Sex
Oesophageal cancer
Gastric cancer
Chemotherapy
Survival
PERIOPERATIVE CHEMOTHERAPY
OPEN-LABEL
ESOPHAGEAL
GENDER
OUTCOMES
RESECTION
RISK

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10.1016/j.ejca.2020.06.005Licence: CC BY-NC-ND

Cite this

Athauda, A., Nankivell, M., Langley, R. E., Alderson, D., Allum, W., Grabsch, H. I., Starling, N., Chau, I., & Cunningham, D. (2020). Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03). European Journal of Cancer, 137, 45-56. https://doi.org/10.1016/j.ejca.2020.06.005

Athauda, Avani ; Nankivell, Matthew ; Langley, Ruth E. ; Alderson, Derek ; Allum, William ; Grabsch, Heike I. ; Starling, Naureen ; Chau, Ian ; Cunningham, David. / Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer : A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03). In: European Journal of Cancer. 2020 ; Vol. 137. pp. 45-56.

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keywords = "Age, Sex, Oesophageal cancer, Gastric cancer, Chemotherapy, Survival, PERIOPERATIVE CHEMOTHERAPY, OPEN-LABEL, ESOPHAGEAL, GENDER, OUTCOMES, RESECTION, RISK",

author = "Avani Athauda and Matthew Nankivell and Langley, {Ruth E.} and Derek Alderson and William Allum and Grabsch, {Heike I.} and Naureen Starling and Ian Chau and David Cunningham",

year = "2020",

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doi = "10.1016/j.ejca.2020.06.005",

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volume = "137",

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Athauda, A, Nankivell, M, Langley, RE, Alderson, D, Allum, W, Grabsch, HI, Starling, N, Chau, I & Cunningham, D 2020, 'Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03)', European Journal of Cancer, vol. 137, pp. 45-56. https://doi.org/10.1016/j.ejca.2020.06.005

Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer : A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03). / Athauda, Avani; Nankivell, Matthew; Langley, Ruth E.; Alderson, Derek; Allum, William; Grabsch, Heike I.; Starling, Naureen; Chau, Ian; Cunningham, David.

In: European Journal of Cancer, Vol. 137, 09.2020, p. 45-56.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer

T2 - A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03)

AU - Athauda, Avani

AU - Nankivell, Matthew

AU - Langley, Ruth E.

AU - Alderson, Derek

AU - Allum, William

AU - Grabsch, Heike I.

AU - Starling, Naureen

AU - Chau, Ian

AU - Cunningham, David

PY - 2020/9

Y1 - 2020/9

KW - Age

KW - Sex

KW - Oesophageal cancer

KW - Gastric cancer

KW - Chemotherapy

KW - Survival

KW - PERIOPERATIVE CHEMOTHERAPY

KW - OPEN-LABEL

KW - ESOPHAGEAL

KW - GENDER

KW - OUTCOMES

KW - RESECTION

KW - RISK

U2 - 10.1016/j.ejca.2020.06.005

DO - 10.1016/j.ejca.2020.06.005

M3 - Article

C2 - 32745964

VL - 137

SP - 45

EP - 56

JO - European Journal of Cancer

JF - European Journal of Cancer

SN - 0959-8049

ER -

Athauda A, Nankivell M, Langley RE, Alderson D, Allum W, Grabsch HI et al. Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03). European Journal of Cancer. 2020 Sep;137:45-56. https://doi.org/10.1016/j.ejca.2020.06.005