Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review

Z. Vinarov, M. Abdallah, J.A.G. Agundez, K. Allegaert, A.W. Basit, M. Braeckmans, J. Ceulemans, M. Corsetti, B.T. Griffin, M. Grimm, D. Keszthelyi, M. Koziolek, C.M. Madla, C. Matthys, L.E. McCoubrey, A. Mitra, C. Reppas, J. Stappaerts, N. Steenackers, N.L. TrevaskisT. Vanuytsel, M. Vertzoni, W. Weitschies, C. Wilson, P. Augustijns*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

11 Citations (Web of Science)
Original languageEnglish
Article number105812
Number of pages33
JournalEuropean Journal of Pharmaceutical Sciences
Volume162
DOIs
Publication statusPublished - 1 Jul 2021

Keywords

  • Variation
  • Fasted and fed state
  • Physiology
  • Pediatrics and geriatrics
  • Diseases
  • Drug formulation
  • PROTON PUMP INHIBITORS
  • HUMAN INTESTINAL FLUID
  • COLONIC BACTERIAL METABOLISM
  • TYROSINE KINASE INHIBITORS
  • OROCECAL TRANSIT-TIME
  • SHORT-BOWEL SYNDROME
  • IN-VITRO
  • ENTEROHEPATIC RECIRCULATION
  • LYMPHATIC TRANSPORT
  • DOSAGE FORMS

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