TY - JOUR
T1 - Impact of CARDIOrespiratory FITness on Arrhythmia Recurrence in Obese Individuals With Atrial Fibrillation The CARDIO-FIT Study
AU - Pathak, Rajeev K.
AU - Elliott, Adrian
AU - Middeldorp, Melissa E.
AU - Meredith, Megan
AU - Mehta, Abhinav B.
AU - Mahajan, Rajiv
AU - Hendriks, Jeroen M. L.
AU - Twomey, Darragh
AU - Kalman, Jonathan M.
AU - Abhayaratna, Walter P.
AU - Lau, Dennis H.
AU - Sanders, Prashanthan
N1 - 10.1016/j.jacc.2015.06.488
PY - 2015
Y1 - 2015
N2 - Background Obesity begets atrial fibrillation (AF). Although cardiorespiratory fitness is protective against incident AF in obese individuals, its effect on AF recurrence or the benefit of cardiorespiratory fitness gain is unknown. Objectives This study sought to evaluate the role of cardiorespiratory fitness and the incremental benefit of cardiorespiratory fitness improvement on rhythm control in obese individuals with AF. Methods Of 1,415 consecutive patients with AF, 825 had a body mass index ≥27 kg/m2 and were offered risk factor management and participation in a tailored exercise program. After exclusions, 308 patients were included in the analysis. Patients underwent exercise stress testing to determine peak metabolic equivalents (METs). To determine a dose response, cardiorespiratory fitness was categorized as: low (100%). Impact of cardiorespiratory fitness gain was ascertained by the objective gain in fitness at final follow-up (≥2 METs vs.
AB - Background Obesity begets atrial fibrillation (AF). Although cardiorespiratory fitness is protective against incident AF in obese individuals, its effect on AF recurrence or the benefit of cardiorespiratory fitness gain is unknown. Objectives This study sought to evaluate the role of cardiorespiratory fitness and the incremental benefit of cardiorespiratory fitness improvement on rhythm control in obese individuals with AF. Methods Of 1,415 consecutive patients with AF, 825 had a body mass index ≥27 kg/m2 and were offered risk factor management and participation in a tailored exercise program. After exclusions, 308 patients were included in the analysis. Patients underwent exercise stress testing to determine peak metabolic equivalents (METs). To determine a dose response, cardiorespiratory fitness was categorized as: low (100%). Impact of cardiorespiratory fitness gain was ascertained by the objective gain in fitness at final follow-up (≥2 METs vs.
KW - atrial fibrillation fitness obesity physical activity risk factors weight loss
U2 - 10.1016/j.jacc.2015.06.488
DO - 10.1016/j.jacc.2015.06.488
M3 - Article
SN - 0735-1097
VL - 66
SP - 985
EP - 996
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 9
ER -