Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium

Dirk W. Donker, Jos G. Maessen, Fons Verheyen, Frans Ramaekers, Roel L. H. M. G. Spatjens, Relma Kuijpers, Christian Rarnakers, Paul M. H. Schiffers, Marc A. Vos, Harry J. G. M. Crijns, Paul G. A. Volders*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)H2324-H2332
JournalAmerican Journal of Physiology-heart and Circulatory Physiology
Issue number5
Publication statusPublished - May 2007


  • hemodynamics
  • myofiber mechanics
  • serial intramural ventricular biopsies
  • cardiomyocyte remodeling
  • ventricular hypertrophy

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