Osteomyelitis is an inflammatory process accompanied
by bone destruction, and is caused by microorganism
infection. The infection can be limited to a single portion
of the bone or can involve several compartments such as
marrow, cortex, periosteum and the surrounding soft
tissue. Osteomyelitis can be (1) spread locally from a focal
source of infection, (2) secondary to vascular insufficiency,
or (3) caused by hematogenous spread of the microorganism from a different source.
For osteomyelitis in the extremities, the most common
pathogen is Staphylococcus aureus. In skull-base osteomyelitis (SBO) it is Pseudomonas aeruginosa (50–90% of cases) [1]. Osteomyelitis of the skull base most often occurs
as a complication of otitis externa, and can be categorized
within the first category of focal infections. However, it is
perceived as a special case due to the severe complications
that can arise, given the location. The bacterial infection
causes bone erosions, and uses fascial planes and venous
sinuses for distant tissue invasion. It then can progress and
spread to the surrounding osseous and soft tissues via the skull base
Original languageEnglish
Pages (from-to)54-62
Number of pages9
JournalMagnetom Flash
Issue number1
Publication statusPublished - 2020

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