Imaging and modeling of acute pressure-induced changes of collagen and elastin microarchitectures in pig and human resistance arteries

Maria Bloksgaard*, Thomas M. Leurgans, Bart Spronck, Maarten H. G. Heusinkveld, Bjarne Thorsted, Kristoffer Rosenstand, Inger Nissen, Ulla M. Hansen, Jonathan R. Brewer, Luis A. Bagatolli, Lars M. Rasmussen, Akhmadjon Irmukhamedov, Koen D. Reesink, Jo G. R. De Mey

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)H164-H178
Number of pages15
JournalAmerican Journal of Physiology-heart and Circulatory Physiology
Volume313
Issue number1
DOIs
Publication statusPublished - Jul 2017

Keywords

  • incremental elastic (Young's) modulus
  • extracellular matrix
  • two-photon excitation fluorescence microscopy
  • collagen recruitment
  • SPONTANEOUSLY HYPERTENSIVE-RATS
  • EXTRACELLULAR-MATRIX
  • CARDIOVASCULAR EVENTS
  • MECHANICAL-PROPERTIES
  • STRUCTURAL ALTERATIONS
  • INDEPENDENT PREDICTOR
  • FUNCTIONAL-CHANGES
  • CORONARY-ARTERIES
  • DIABETES-MELLITUS
  • CAROTID ARTERIES

Cite this

Bloksgaard, M., Leurgans, T. M., Spronck, B., Heusinkveld, M. H. G., Thorsted, B., Rosenstand, K., Nissen, I., Hansen, U. M., Brewer, J. R., Bagatolli, L. A., Rasmussen, L. M., Irmukhamedov, A., Reesink, K. D., & De Mey, J. G. R. (2017). Imaging and modeling of acute pressure-induced changes of collagen and elastin microarchitectures in pig and human resistance arteries. American Journal of Physiology-heart and Circulatory Physiology, 313(1), H164-H178. https://doi.org/10.1152/ajpheart.00110.2017