IL-1/inhibitory kappa B kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease

Xi Qian, Reem Aboushousha, Cheryl van de Wetering, Shi B. Chia, Eyal Amiel, Robert W. Schneider, Jos L. J. van der Velden, Karolyn G. Lahue, Daisy A. Hoagland, Dylan T. Casey, Nirav Daphtary, Jennifer L. Ather, Matthew J. Randall, Minara Aliyeva, Kendall E. Black, David G. Chapman, Lennart K. A. Lundblad, David H. McMillan, Anne E. Dixon, Vikas AnathyCharles G. Irvin, Matthew E. Poynter, Emiel F. M. Wouters, Pamela M. Vacek, Monique Henket, Florence Schleich, Renaud Louis, Albert van der Vliet, Yvonne M. W. Janssen-Heininger

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)435-450.e10
Number of pages26
JournalJournal of Allergy and Clinical Immunology
Volume142
Issue number2
DOIs
Publication statusPublished - 1 Aug 2018

Keywords

  • Asthma
  • house dust mite
  • glycolysis
  • IL-1
  • inhibitor of kappa B kinase epsilon
  • lactate
  • lactate dehydrogenase A
  • DENDRITIC CELL ACTIVATION
  • HOUSE-DUST MITE
  • NLRP3 INFLAMMASOME
  • SEVERE ASTHMA
  • MURINE MODEL
  • LUNG-CANCER
  • INTERLEUKIN-1
  • HYPERRESPONSIVENESS
  • LACTATE
  • MICE
  • RESPONSES
  • METABOLISM
  • CELL ACTIVATION
  • INFLAMMATION
  • ASTHMA
  • ACTIVATION PROMOTES

Cite this

Qian, Xi ; Aboushousha, Reem ; van de Wetering, Cheryl ; Chia, Shi B. ; Amiel, Eyal ; Schneider, Robert W. ; van der Velden, Jos L. J. ; Lahue, Karolyn G. ; Hoagland, Daisy A. ; Casey, Dylan T. ; Daphtary, Nirav ; Ather, Jennifer L. ; Randall, Matthew J. ; Aliyeva, Minara ; Black, Kendall E. ; Chapman, David G. ; Lundblad, Lennart K. A. ; McMillan, David H. ; Dixon, Anne E. ; Anathy, Vikas ; Irvin, Charles G. ; Poynter, Matthew E. ; Wouters, Emiel F. M. ; Vacek, Pamela M. ; Henket, Monique ; Schleich, Florence ; Louis, Renaud ; van der Vliet, Albert ; Janssen-Heininger, Yvonne M. W. / IL-1/inhibitory kappa B kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease. In: Journal of Allergy and Clinical Immunology. 2018 ; Vol. 142, No. 2. pp. 435-450.e10.
@article{6be1e3fe4aba4a60a183233a452f95bd,
title = "IL-1/inhibitory kappa B kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease",
keywords = "Asthma, house dust mite, glycolysis, IL-1, inhibitor of kappa B kinase epsilon, lactate, lactate dehydrogenase A, DENDRITIC CELL ACTIVATION, HOUSE-DUST MITE, NLRP3 INFLAMMASOME, SEVERE ASTHMA, MURINE MODEL, LUNG-CANCER, INTERLEUKIN-1, HYPERRESPONSIVENESS, LACTATE, MICE, RESPONSES, METABOLISM, CELL ACTIVATION, INFLAMMATION, ASTHMA, ACTIVATION PROMOTES",
author = "Xi Qian and Reem Aboushousha and {van de Wetering}, Cheryl and Chia, {Shi B.} and Eyal Amiel and Schneider, {Robert W.} and {van der Velden}, {Jos L. J.} and Lahue, {Karolyn G.} and Hoagland, {Daisy A.} and Casey, {Dylan T.} and Nirav Daphtary and Ather, {Jennifer L.} and Randall, {Matthew J.} and Minara Aliyeva and Black, {Kendall E.} and Chapman, {David G.} and Lundblad, {Lennart K. A.} and McMillan, {David H.} and Dixon, {Anne E.} and Vikas Anathy and Irvin, {Charles G.} and Poynter, {Matthew E.} and Wouters, {Emiel F. M.} and Vacek, {Pamela M.} and Monique Henket and Florence Schleich and Renaud Louis and {van der Vliet}, Albert and Janssen-Heininger, {Yvonne M. W.}",
year = "2018",
month = "8",
day = "1",
doi = "10.1016/j.jaci.2017.08.043",
language = "English",
volume = "142",
pages = "435--450.e10",
journal = "Journal of Allergy and Clinical Immunology",
issn = "0091-6749",
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number = "2",

}

Qian, X, Aboushousha, R, van de Wetering, C, Chia, SB, Amiel, E, Schneider, RW, van der Velden, JLJ, Lahue, KG, Hoagland, DA, Casey, DT, Daphtary, N, Ather, JL, Randall, MJ, Aliyeva, M, Black, KE, Chapman, DG, Lundblad, LKA, McMillan, DH, Dixon, AE, Anathy, V, Irvin, CG, Poynter, ME, Wouters, EFM, Vacek, PM, Henket, M, Schleich, F, Louis, R, van der Vliet, A & Janssen-Heininger, YMW 2018, 'IL-1/inhibitory kappa B kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease', Journal of Allergy and Clinical Immunology, vol. 142, no. 2, pp. 435-450.e10. https://doi.org/10.1016/j.jaci.2017.08.043

IL-1/inhibitory kappa B kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease. / Qian, Xi; Aboushousha, Reem; van de Wetering, Cheryl; Chia, Shi B.; Amiel, Eyal; Schneider, Robert W.; van der Velden, Jos L. J.; Lahue, Karolyn G.; Hoagland, Daisy A.; Casey, Dylan T.; Daphtary, Nirav; Ather, Jennifer L.; Randall, Matthew J.; Aliyeva, Minara; Black, Kendall E.; Chapman, David G.; Lundblad, Lennart K. A.; McMillan, David H.; Dixon, Anne E.; Anathy, Vikas; Irvin, Charles G.; Poynter, Matthew E.; Wouters, Emiel F. M.; Vacek, Pamela M.; Henket, Monique; Schleich, Florence; Louis, Renaud; van der Vliet, Albert; Janssen-Heininger, Yvonne M. W.

In: Journal of Allergy and Clinical Immunology, Vol. 142, No. 2, 01.08.2018, p. 435-450.e10.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - IL-1/inhibitory kappa B kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease

AU - Qian, Xi

AU - Aboushousha, Reem

AU - van de Wetering, Cheryl

AU - Chia, Shi B.

AU - Amiel, Eyal

AU - Schneider, Robert W.

AU - van der Velden, Jos L. J.

AU - Lahue, Karolyn G.

AU - Hoagland, Daisy A.

AU - Casey, Dylan T.

AU - Daphtary, Nirav

AU - Ather, Jennifer L.

AU - Randall, Matthew J.

AU - Aliyeva, Minara

AU - Black, Kendall E.

AU - Chapman, David G.

AU - Lundblad, Lennart K. A.

AU - McMillan, David H.

AU - Dixon, Anne E.

AU - Anathy, Vikas

AU - Irvin, Charles G.

AU - Poynter, Matthew E.

AU - Wouters, Emiel F. M.

AU - Vacek, Pamela M.

AU - Henket, Monique

AU - Schleich, Florence

AU - Louis, Renaud

AU - van der Vliet, Albert

AU - Janssen-Heininger, Yvonne M. W.

PY - 2018/8/1

Y1 - 2018/8/1

KW - Asthma

KW - house dust mite

KW - glycolysis

KW - IL-1

KW - inhibitor of kappa B kinase epsilon

KW - lactate

KW - lactate dehydrogenase A

KW - DENDRITIC CELL ACTIVATION

KW - HOUSE-DUST MITE

KW - NLRP3 INFLAMMASOME

KW - SEVERE ASTHMA

KW - MURINE MODEL

KW - LUNG-CANCER

KW - INTERLEUKIN-1

KW - HYPERRESPONSIVENESS

KW - LACTATE

KW - MICE

KW - RESPONSES

KW - METABOLISM

KW - CELL ACTIVATION

KW - INFLAMMATION

KW - ASTHMA

KW - ACTIVATION PROMOTES

U2 - 10.1016/j.jaci.2017.08.043

DO - 10.1016/j.jaci.2017.08.043

M3 - Article

VL - 142

SP - 435-450.e10

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

SN - 0091-6749

IS - 2

ER -