IFN Lambda 3/4 locus polymorphisms and IFN Lambda 3 circulating levels are associated with COPD severity and outcomes

Adrian Egli; Jyotshna Mandal; Desiree M. Schumann; Michael Roth; Brad Thomas; D. Lorne Tyrrell; Francesco Blasi; Kostantinos Kostikas; Wim Boersma; Branislava Milenkovic; Alicia Lacoma; Katharina Rentsch; Gernot G. U. Rohde; Renaud Louis; Joachim G. Aerts; Tobias Welte; Antoni Torres; Michael Tamm; Daiana Stolz

doi:10.1186/s12890-018-0616-6

IFN Lambda 3/4 locus polymorphisms and IFN Lambda 3 circulating levels are associated with COPD severity and outcomes

Adrian Egli, Jyotshna Mandal, Desiree M. Schumann^*, Michael Roth, Brad Thomas, D. Lorne Tyrrell, Francesco Blasi, Kostantinos Kostikas, Wim Boersma, Branislava Milenkovic, Alicia Lacoma, Katharina Rentsch, Gernot G. U. Rohde, Renaud Louis, Joachim G. Aerts, Tobias Welte, Antoni Torres, Michael Tamm, Daiana Stolz

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	51
Number of pages	9
Journal	BMC Pulmonary Medicine
Volume	18
DOIs	https://doi.org/10.1186/s12890-018-0616-6
Publication status	Published - 21 Mar 2018

Keywords

Interleukin 28B
Cohort
Mortality
Biomarker
Single nucleotide polymorphisms
CHRONIC HEPATITIS-C
OBSTRUCTIVE PULMONARY-DISEASE
GENOME-WIDE ASSOCIATION
GENETIC-VARIATION
INTERFERON-LAMBDA
IL28B
ASTHMA
EXACERBATION
EXPRESSION
BIOMARKERS

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10.1186/s12890-018-0616-6

https://bmcpulmmed.biomedcentral.com/track/pdf/10.1186/s12890-018-0616-6

Cite this

Egli, A., Mandal, J., Schumann, D. M., Roth, M., Thomas, B., Tyrrell, D. L., Blasi, F., Kostikas, K., Boersma, W., Milenkovic, B., Lacoma, A., Rentsch, K., Rohde, G. G. U., Louis, R., Aerts, J. G., Welte, T., Torres, A., Tamm, M., & Stolz, D. (2018). IFN Lambda 3/4 locus polymorphisms and IFN Lambda 3 circulating levels are associated with COPD severity and outcomes. BMC Pulmonary Medicine, 18, [51]. https://doi.org/10.1186/s12890-018-0616-6

Egli, Adrian ; Mandal, Jyotshna ; Schumann, Desiree M. ; Roth, Michael ; Thomas, Brad ; Tyrrell, D. Lorne ; Blasi, Francesco ; Kostikas, Kostantinos ; Boersma, Wim ; Milenkovic, Branislava ; Lacoma, Alicia ; Rentsch, Katharina ; Rohde, Gernot G. U. ; Louis, Renaud ; Aerts, Joachim G. ; Welte, Tobias ; Torres, Antoni ; Tamm, Michael ; Stolz, Daiana. / IFN Lambda 3/4 locus polymorphisms and IFN Lambda 3 circulating levels are associated with COPD severity and outcomes. In: BMC Pulmonary Medicine. 2018 ; Vol. 18.

@article{b47b87653c584749be0670442079d771,

title = "IFN Lambda 3/4 locus polymorphisms and IFN Lambda 3 circulating levels are associated with COPD severity and outcomes",

keywords = "Interleukin 28B, Cohort, Mortality, Biomarker, Single nucleotide polymorphisms, CHRONIC HEPATITIS-C, OBSTRUCTIVE PULMONARY-DISEASE, GENOME-WIDE ASSOCIATION, GENETIC-VARIATION, INTERFERON-LAMBDA, IL28B, ASTHMA, EXACERBATION, EXPRESSION, BIOMARKERS",

author = "Adrian Egli and Jyotshna Mandal and Schumann, {Desiree M.} and Michael Roth and Brad Thomas and Tyrrell, {D. Lorne} and Francesco Blasi and Kostantinos Kostikas and Wim Boersma and Branislava Milenkovic and Alicia Lacoma and Katharina Rentsch and Rohde, {Gernot G. U.} and Renaud Louis and Aerts, {Joachim G.} and Tobias Welte and Antoni Torres and Michael Tamm and Daiana Stolz",

year = "2018",

month = mar,

day = "21",

doi = "10.1186/s12890-018-0616-6",

language = "English",

volume = "18",

journal = "BMC Pulmonary Medicine",

issn = "1471-2466",

publisher = "BioMed Central Ltd",

}

Egli, A, Mandal, J, Schumann, DM, Roth, M, Thomas, B, Tyrrell, DL, Blasi, F, Kostikas, K, Boersma, W, Milenkovic, B, Lacoma, A, Rentsch, K, Rohde, GGU, Louis, R, Aerts, JG, Welte, T, Torres, A, Tamm, M & Stolz, D 2018, 'IFN Lambda 3/4 locus polymorphisms and IFN Lambda 3 circulating levels are associated with COPD severity and outcomes', BMC Pulmonary Medicine, vol. 18, 51. https://doi.org/10.1186/s12890-018-0616-6

IFN Lambda 3/4 locus polymorphisms and IFN Lambda 3 circulating levels are associated with COPD severity and outcomes. / Egli, Adrian; Mandal, Jyotshna; Schumann, Desiree M.; Roth, Michael; Thomas, Brad; Tyrrell, D. Lorne; Blasi, Francesco; Kostikas, Kostantinos; Boersma, Wim; Milenkovic, Branislava; Lacoma, Alicia; Rentsch, Katharina; Rohde, Gernot G. U.; Louis, Renaud; Aerts, Joachim G.; Welte, Tobias; Torres, Antoni; Tamm, Michael; Stolz, Daiana.

In: BMC Pulmonary Medicine, Vol. 18, 51, 21.03.2018.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - IFN Lambda 3/4 locus polymorphisms and IFN Lambda 3 circulating levels are associated with COPD severity and outcomes

AU - Egli, Adrian

AU - Mandal, Jyotshna

AU - Schumann, Desiree M.

AU - Roth, Michael

AU - Thomas, Brad

AU - Tyrrell, D. Lorne

AU - Blasi, Francesco

AU - Kostikas, Kostantinos

AU - Boersma, Wim

AU - Milenkovic, Branislava

AU - Lacoma, Alicia

AU - Rentsch, Katharina

AU - Rohde, Gernot G. U.

AU - Louis, Renaud

AU - Aerts, Joachim G.

AU - Welte, Tobias

AU - Torres, Antoni

AU - Tamm, Michael

AU - Stolz, Daiana

PY - 2018/3/21

Y1 - 2018/3/21

KW - Interleukin 28B

KW - Cohort

KW - Mortality

KW - Biomarker

KW - Single nucleotide polymorphisms

KW - CHRONIC HEPATITIS-C

KW - OBSTRUCTIVE PULMONARY-DISEASE

KW - GENOME-WIDE ASSOCIATION

KW - GENETIC-VARIATION

KW - INTERFERON-LAMBDA

KW - IL28B

KW - ASTHMA

KW - EXACERBATION

KW - EXPRESSION

KW - BIOMARKERS

U2 - 10.1186/s12890-018-0616-6

DO - 10.1186/s12890-018-0616-6

M3 - Article

VL - 18

JO - BMC Pulmonary Medicine

JF - BMC Pulmonary Medicine

SN - 1471-2466

M1 - 51

ER -