Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative

Sabrina M. Nielsen; Peter Tugwell; Maarten P. T. de Wit; Maarten Boers; Dorcas E. Beaton; Thasia G. Woodworth; Reuben Escorpizo; Beverley Shea; Karine Toupin-April; Francis Guillemin; Vibeke Strand; Jasvinder A. Singh; Margreet Kloppenburg; Daniel E. Furst; George A. Wells; Josef S. Smolen; Richard Vesely; Annelies Boonen; Helene Storgaard; Marieke Voshaar; Lyn March; Robin Christensen; Contextual Factors Working Group

doi:10.3899/jrheum.181081

Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative

Sabrina M. Nielsen, Peter Tugwell, Maarten P. T. de Wit, Maarten Boers, Dorcas E. Beaton, Thasia G. Woodworth, Reuben Escorpizo, Beverley Shea, Karine Toupin-April, Francis Guillemin, Vibeke Strand, Jasvinder A. Singh, Margreet Kloppenburg, Daniel E. Furst, George A. Wells, Josef S. Smolen, Richard Vesely, Annelies Boonen, Helene Storgaard, Marieke VoshaarLyn March, Robin Christensen^*, Contextual Factors Working Group

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Web of Science)

Abstract

Objective. The Contextual Factors Working Group aims to provide guidance on addressing contextual factors in rheumatology trials within OMERACT.

Methods. During the Special Interest Group session at OMERACT 2018, preliminary results were presented from a case scenario survey and semistructured interviews, including contextual factors mentioned in these. A group-based exercise sought to identify and rank important generic contextual factors.

Results. A total of 79 candidate factors were listed. Across the 3 groups, gender/sex, comorbidities, and the healthcare system were ranked as most important.

Conclusion. The identified important contextual factor domains may be considered a provisional list pending further research.

Original language	English
Pages (from-to)	1159-1163
Number of pages	5
Journal	Journal of Rheumatology
Volume	46
Issue number	9
DOIs	https://doi.org/10.3899/jrheum.181081
Publication status	Published - 1 Sept 2019
Event	Outcome Measures in Rheumatology Conference (OMERACT) - Terrigal, Australia Duration: 15 May 2018 → 18 May 2018

Keywords

OMERACT
CLINICAL TRIALS
OUTCOMES
RHEUMATIC DISEASES

Access to Document

10.3899/jrheum.181081

Cite this

Nielsen, S. M., Tugwell, P., de Wit, M. P. T., Boers, M., Beaton, D. E., Woodworth, T. G., Escorpizo, R., Shea, B., Toupin-April, K., Guillemin, F., Strand, V., Singh, J. A., Kloppenburg, M., Furst, D. E., Wells, G. A., Smolen, J. S., Vesely, R., Boonen, A., Storgaard, H., ... Contextual Factors Working Group (2019). Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative. Journal of Rheumatology, 46(9), 1159-1163. https://doi.org/10.3899/jrheum.181081

@article{a577f99ce5464a57b9817a3517596165,

title = "Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative",

abstract = "Objective. The Contextual Factors Working Group aims to provide guidance on addressing contextual factors in rheumatology trials within OMERACT.Methods. During the Special Interest Group session at OMERACT 2018, preliminary results were presented from a case scenario survey and semistructured interviews, including contextual factors mentioned in these. A group-based exercise sought to identify and rank important generic contextual factors.Results. A total of 79 candidate factors were listed. Across the 3 groups, gender/sex, comorbidities, and the healthcare system were ranked as most important.Conclusion. The identified important contextual factor domains may be considered a provisional list pending further research.",

keywords = "OMERACT, CLINICAL TRIALS, OUTCOMES, RHEUMATIC DISEASES",

author = "Nielsen, {Sabrina M.} and Peter Tugwell and {de Wit}, {Maarten P. T.} and Maarten Boers and Beaton, {Dorcas E.} and Woodworth, {Thasia G.} and Reuben Escorpizo and Beverley Shea and Karine Toupin-April and Francis Guillemin and Vibeke Strand and Singh, {Jasvinder A.} and Margreet Kloppenburg and Furst, {Daniel E.} and Wells, {George A.} and Smolen, {Josef S.} and Richard Vesely and Annelies Boonen and Helene Storgaard and Marieke Voshaar and Lyn March and Robin Christensen and {Contextual Factors Working Group}",

year = "2019",

month = sep,

day = "1",

doi = "10.3899/jrheum.181081",

language = "English",

volume = "46",

pages = "1159--1163",

journal = "Journal of Rheumatology",

issn = "0315-162X",

publisher = "Journal of Rheumatology Publishing Co. Ltd.",

number = "9",

note = "Outcome Measures in Rheumatology Conference (OMERACT) ; Conference date: 15-05-2018 Through 18-05-2018",

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Nielsen, SM, Tugwell, P, de Wit, MPT, Boers, M, Beaton, DE, Woodworth, TG, Escorpizo, R, Shea, B, Toupin-April, K, Guillemin, F, Strand, V, Singh, JA, Kloppenburg, M, Furst, DE, Wells, GA, Smolen, JS, Vesely, R, Boonen, A, Storgaard, H, Voshaar, M, March, L, Christensen, R & Contextual Factors Working Group 2019, 'Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative', Journal of Rheumatology, vol. 46, no. 9, pp. 1159-1163. https://doi.org/10.3899/jrheum.181081

TY - JOUR

T1 - Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology

T2 - Outcome Measures in Rheumatology Conference (OMERACT)

AU - Nielsen, Sabrina M.

AU - Tugwell, Peter

AU - de Wit, Maarten P. T.

AU - Boers, Maarten

AU - Beaton, Dorcas E.

AU - Woodworth, Thasia G.

AU - Escorpizo, Reuben

AU - Shea, Beverley

AU - Toupin-April, Karine

AU - Guillemin, Francis

AU - Strand, Vibeke

AU - Singh, Jasvinder A.

AU - Kloppenburg, Margreet

AU - Furst, Daniel E.

AU - Wells, George A.

AU - Smolen, Josef S.

AU - Vesely, Richard

AU - Boonen, Annelies

AU - Storgaard, Helene

AU - Voshaar, Marieke

AU - March, Lyn

AU - Christensen, Robin

AU - Contextual Factors Working Group

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Objective. The Contextual Factors Working Group aims to provide guidance on addressing contextual factors in rheumatology trials within OMERACT.Methods. During the Special Interest Group session at OMERACT 2018, preliminary results were presented from a case scenario survey and semistructured interviews, including contextual factors mentioned in these. A group-based exercise sought to identify and rank important generic contextual factors.Results. A total of 79 candidate factors were listed. Across the 3 groups, gender/sex, comorbidities, and the healthcare system were ranked as most important.Conclusion. The identified important contextual factor domains may be considered a provisional list pending further research.

AB - Objective. The Contextual Factors Working Group aims to provide guidance on addressing contextual factors in rheumatology trials within OMERACT.Methods. During the Special Interest Group session at OMERACT 2018, preliminary results were presented from a case scenario survey and semistructured interviews, including contextual factors mentioned in these. A group-based exercise sought to identify and rank important generic contextual factors.Results. A total of 79 candidate factors were listed. Across the 3 groups, gender/sex, comorbidities, and the healthcare system were ranked as most important.Conclusion. The identified important contextual factor domains may be considered a provisional list pending further research.

KW - OMERACT

KW - CLINICAL TRIALS

KW - OUTCOMES

KW - RHEUMATIC DISEASES

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DO - 10.3899/jrheum.181081

M3 - Article

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SN - 0315-162X

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JO - Journal of Rheumatology

JF - Journal of Rheumatology

IS - 9

Y2 - 15 May 2018 through 18 May 2018

ER -