Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Cross-Disorder Group of the Psychiatric Genomics, C.; Jim van Os; Inez Germeys; Don Linszen; A. Reif

doi:10.1016/S0140-6736(12)62129-1

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Cross-Disorder Group of the Psychiatric Genomics, C., Jim van Os, Inez Germeys, Don Linszen, A. Reif

Research output: Contribution to journal › Article › Academic › peer-review

1839 Citations (Web of Science)

Abstract

Background findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specific variants underlying genetic effects shared between the five disorders in the psychiatric genomics consortium: autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia.

Original language	English
Pages (from-to)	1371-1379
Journal	Lancet
Volume	381
Issue number	9875
DOIs	https://doi.org/10.1016/S0140-6736(12)62129-1
Publication status	Published - 20 Apr 2013

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10.1016/S0140-6736(12)62129-1

Cite this

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title = "Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis",

abstract = "Background findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specific variants underlying genetic effects shared between the five disorders in the psychiatric genomics consortium: autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia.",

author = "Smoller, {Jordan W.} and Nicholas Craddock and Kenneth Kendler and Lee, {Phil Hyoun} and Neale, {Benjamin M.} and Nurnberger, {John I.} and Stephan Ripke and Susan Santangelo and {Cross-Disorder Group of the Psychiatric Genomics, C.} and {van Os}, Jim and Inez Germeys and Don Linszen and A. Reif and Sullivan, {Patrick F.}",

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T1 - Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

AU - Smoller, Jordan W.

AU - Craddock, Nicholas

AU - Kendler, Kenneth

AU - Lee, Phil Hyoun

AU - Neale, Benjamin M.

AU - Nurnberger, John I.

AU - Ripke, Stephan

AU - Santangelo, Susan

AU - Cross-Disorder Group of the Psychiatric Genomics, C.

AU - van Os, Jim

AU - Germeys, Inez

AU - Linszen, Don

AU - Reif, A.

AU - Sullivan, Patrick F.

PY - 2013/4/20

Y1 - 2013/4/20

N2 - Background findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specific variants underlying genetic effects shared between the five disorders in the psychiatric genomics consortium: autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia.

AB - Background findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specific variants underlying genetic effects shared between the five disorders in the psychiatric genomics consortium: autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia.

U2 - 10.1016/S0140-6736(12)62129-1

DO - 10.1016/S0140-6736(12)62129-1

M3 - Article

VL - 381

SP - 1371

EP - 1379

JO - Lancet

JF - Lancet

SN - 0140-6736

IS - 9875

ER -