I-131-MIBG therapies

S. Voo, J. Bucerius, F.M. Mottaghy

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Metaiodobenzylguanidine (MIBG) is a tracer that selectively targets neuroendocrine cells. On this basis, radiolabeled iodinated-MIBG (I-131-MIBG) has been introduced as a molecular nuclear therapy in the management of neuroendocrine tumors, including neuroblastoma, pheochromocytoma, paraganglioma, neuroendocrine carcinomas, and other rare neuroendocrine tumors. Extensive work has been addressed to develop I-131-MIBG therapy: doses, therapeutic schemes, and efficiency. In this paper, we present an overview on I-131-MIBG therapy, with main focus on different aspects how to perform this treatment.
Original languageEnglish
Pages (from-to)238-45
JournalMethods
Volume55
Issue number3
DOIs
Publication statusPublished - 1 Jan 2011

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