Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DBD)

Zoltan Czigany; Wenzel Schoening; Tom Florian Ulmer; Jan Bednarsch; Iakovos Amygdalos; Thorsten Cramer; Xavier Rogiers; Irinel Popescu; Florin Botea; Jiri Fronek; Daniela Kroy; Alexander Koch; Frank Tacke; Christian Trautwein; Rene H. Tolba; Marc Hein; Ger H. Koek; Cornelis H. C. Dejong; Ulf Peter Neumann; Georg Lurje

doi:10.1136/bmjopen-2017-017558

Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DBD)

Zoltan Czigany, Wenzel Schoening, Tom Florian Ulmer, Jan Bednarsch, Iakovos Amygdalos, Thorsten Cramer, Xavier Rogiers, Irinel Popescu, Florin Botea, Jiri Fronek, Daniela Kroy, Alexander Koch, Frank Tacke, Christian Trautwein, Rene H. Tolba, Marc Hein, Ger H. Koek, Cornelis H. C. Dejong, Ulf Peter Neumann, Georg Lurje^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	017558
Number of pages	9
Journal	BMJ Open
Volume	7
Issue number	10
DOIs	https://doi.org/10.1136/bmjopen-2017-017558
Publication status	Published - Oct 2017

Keywords

ISCHEMIA-REPERFUSION INJURY
PORTAL-VEIN PERFUSION
STATIC COLD-STORAGE
CIRCULATORY DEATH
CARDIAC DEATH
GRAFTS
PRESERVATION
MODEL
VALIDATION
MECHANISMS

Access to Document

10.1136/bmjopen-2017-017558

Cite this

Czigany, Z., Schoening, W., Ulmer, T. F., Bednarsch, J., Amygdalos, I., Cramer, T., Rogiers, X., Popescu, I., Botea, F., Fronek, J., Kroy, D., Koch, A., Tacke, F., Trautwein, C., Tolba, R. H., Hein, M., Koek, G. H., Dejong, C. H. C., Neumann, U. P., & Lurje, G. (2017). Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DBD). BMJ Open, 7(10), [017558]. https://doi.org/10.1136/bmjopen-2017-017558

Czigany, Zoltan ; Schoening, Wenzel ; Ulmer, Tom Florian ; Bednarsch, Jan ; Amygdalos, Iakovos ; Cramer, Thorsten ; Rogiers, Xavier ; Popescu, Irinel ; Botea, Florin ; Fronek, Jiri ; Kroy, Daniela ; Koch, Alexander ; Tacke, Frank ; Trautwein, Christian ; Tolba, Rene H. ; Hein, Marc ; Koek, Ger H. ; Dejong, Cornelis H. C. ; Neumann, Ulf Peter ; Lurje, Georg. / Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD) : a prospective multicentre randomised controlled trial (HOPE ECD-DBD). In: BMJ Open. 2017 ; Vol. 7, No. 10.

@article{bc0599ac624940298736af7fe9b43023,

title = "Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DBD)",

keywords = "ISCHEMIA-REPERFUSION INJURY, PORTAL-VEIN PERFUSION, STATIC COLD-STORAGE, CIRCULATORY DEATH, CARDIAC DEATH, GRAFTS, PRESERVATION, MODEL, VALIDATION, MECHANISMS",

author = "Zoltan Czigany and Wenzel Schoening and Ulmer, {Tom Florian} and Jan Bednarsch and Iakovos Amygdalos and Thorsten Cramer and Xavier Rogiers and Irinel Popescu and Florin Botea and Jiri Fronek and Daniela Kroy and Alexander Koch and Frank Tacke and Christian Trautwein and Tolba, {Rene H.} and Marc Hein and Koek, {Ger H.} and Dejong, {Cornelis H. C.} and Neumann, {Ulf Peter} and Georg Lurje",

year = "2017",

month = oct,

doi = "10.1136/bmjopen-2017-017558",

language = "English",

volume = "7",

journal = "BMJ Open",

issn = "2044-6055",

publisher = "BMJ Publishing Group",

number = "10",

}

Czigany, Z, Schoening, W, Ulmer, TF, Bednarsch, J, Amygdalos, I, Cramer, T, Rogiers, X, Popescu, I, Botea, F, Fronek, J, Kroy, D, Koch, A, Tacke, F, Trautwein, C, Tolba, RH, Hein, M, Koek, GH , Dejong, CHC , Neumann, UP & Lurje, G 2017, 'Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DBD)', BMJ Open, vol. 7, no. 10, 017558. https://doi.org/10.1136/bmjopen-2017-017558

Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD) : a prospective multicentre randomised controlled trial (HOPE ECD-DBD). / Czigany, Zoltan; Schoening, Wenzel; Ulmer, Tom Florian; Bednarsch, Jan; Amygdalos, Iakovos; Cramer, Thorsten; Rogiers, Xavier; Popescu, Irinel; Botea, Florin; Fronek, Jiri; Kroy, Daniela; Koch, Alexander; Tacke, Frank; Trautwein, Christian; Tolba, Rene H.; Hein, Marc; Koek, Ger H.; Dejong, Cornelis H. C.; Neumann, Ulf Peter; Lurje, Georg.

In: BMJ Open, Vol. 7, No. 10, 017558, 10.2017.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD)

T2 - a prospective multicentre randomised controlled trial (HOPE ECD-DBD)

AU - Czigany, Zoltan

AU - Schoening, Wenzel

AU - Ulmer, Tom Florian

AU - Bednarsch, Jan

AU - Amygdalos, Iakovos

AU - Cramer, Thorsten

AU - Rogiers, Xavier

AU - Popescu, Irinel

AU - Botea, Florin

AU - Fronek, Jiri

AU - Kroy, Daniela

AU - Koch, Alexander

AU - Tacke, Frank

AU - Trautwein, Christian

AU - Tolba, Rene H.

AU - Hein, Marc

AU - Koek, Ger H.

AU - Dejong, Cornelis H. C.

AU - Neumann, Ulf Peter

AU - Lurje, Georg

PY - 2017/10

Y1 - 2017/10

KW - ISCHEMIA-REPERFUSION INJURY

KW - PORTAL-VEIN PERFUSION

KW - STATIC COLD-STORAGE

KW - CIRCULATORY DEATH

KW - CARDIAC DEATH

KW - GRAFTS

KW - PRESERVATION

KW - MODEL

KW - VALIDATION

KW - MECHANISMS

U2 - 10.1136/bmjopen-2017-017558

DO - 10.1136/bmjopen-2017-017558

M3 - Article

VL - 7

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 10

M1 - 017558

ER -

Czigany Z, Schoening W, Ulmer TF, Bednarsch J, Amygdalos I, Cramer T et al. Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DBD). BMJ Open. 2017 Oct;7(10). 017558. https://doi.org/10.1136/bmjopen-2017-017558