Hypobaric Hypoxia Causes Elevated Thrombin Generation Mediated by FVIII that is Balanced by Decreased Platelet Activation

Cecile H. Kicken*, Marisa Ninivaggi, Joke Konings, Martijn Moorlag, Dana Huskens, Jasper A. Remijn, Saartje Bloemen, Marcus D. Lance, Bas De Laat

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)883-892
Number of pages10
JournalThrombosis and Haemostasis
Volume118
Issue number5
DOIs
Publication statusPublished - 1 May 2018

Keywords

  • hypoxia
  • thrombin generation
  • platelet activation
  • CALIBRATED AUTOMATED THROMBOGRAM
  • DEEP VENOUS THROMBOSIS
  • HIGH-ALTITUDE
  • FIBRINOGEN LEVELS
  • HEART-DISEASE
  • EXTENDED STAY
  • HUMAN-BEINGS
  • WHOLE-BLOOD
  • RISK-FACTOR
  • AIR-TRAVEL

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