Hypobaric Hypoxia Causes Elevated Thrombin Generation Mediated by FVIII that is Balanced by Decreased Platelet Activation

Cecile H. Kicken, Marisa Ninivaggi, Joke Konings, Martijn Moorlag, Dana Huskens, Jasper A. Remijn, Saartje Bloemen, Marcus D. Lance, Bas De Laat

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)883-892
Number of pages10
JournalThrombosis and Haemostasis
Volume118
Issue number5
DOIs
Publication statusPublished - 1 May 2018

Keywords

  • hypoxia
  • thrombin generation
  • platelet activation
  • CALIBRATED AUTOMATED THROMBOGRAM
  • DEEP VENOUS THROMBOSIS
  • HIGH-ALTITUDE
  • FIBRINOGEN LEVELS
  • HEART-DISEASE
  • EXTENDED STAY
  • HUMAN-BEINGS
  • WHOLE-BLOOD
  • RISK-FACTOR
  • AIR-TRAVEL

Cite this

Kicken, C. H., Ninivaggi, M., Konings, J., Moorlag, M., Huskens, D., Remijn, J. A., Bloemen, S., Lance, M. D., & De Laat, B. (2018). Hypobaric Hypoxia Causes Elevated Thrombin Generation Mediated by FVIII that is Balanced by Decreased Platelet Activation. Thrombosis and Haemostasis, 118(5), 883-892. https://doi.org/10.1055/s-0038-1641566