Hypertension and the renin-angiotensin-aldosterone system

Elena Kaschina; Ulrike M. Steckelings; Thomas Unger

doi:10.1016/B978-0-12-801238-3.03969-6

Hypertension and the renin-angiotensin-aldosterone system

Elena Kaschina, Ulrike M. Steckelings, Thomas Unger

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

Abstract

Hypertension is defined as a systolic blood pressure > 140 mmHg or a diastolic blood pressure > 90 mmHg. Renin is a key enzyme of the renin-angiotensin-aldosterone system (RAAS), cleaving angiotensinogen to angiotensin I and, thereby, having an impact on the synthesis rate of the effector hormone of the RAAS, angiotensin II. The RAAS is a hormone system that plays a central role in the control of sodium secretion, fluid volume, and vascular tone, thus controlling blood pressure.

Original language	English
Title of host publication	Encyclopedia of Endocrine Diseases
Editors	Ilpo Huhtaniemi
Publisher	Elsevier
Pages	505-510
Number of pages	6
ISBN (Electronic)	9780128122006
ISBN (Print)	9780128121993
DOIs	https://doi.org/10.1016/B978-0-12-801238-3.03969-6
Publication status	Published - 1 Jan 2018

Keywords

Aldosterone
Angiotensin receptors
Biosynthesis
Hypertension
Renin-angiotensin system

Access to Document

10.1016/B978-0-12-801238-3.03969-6

Cite this

@inbook{9de7ea0e6a5743938331c59149b64ee8,

title = "Hypertension and the renin-angiotensin-aldosterone system",

abstract = "Hypertension is defined as a systolic blood pressure > 140 mmHg or a diastolic blood pressure > 90 mmHg. Renin is a key enzyme of the renin-angiotensin-aldosterone system (RAAS), cleaving angiotensinogen to angiotensin I and, thereby, having an impact on the synthesis rate of the effector hormone of the RAAS, angiotensin II. The RAAS is a hormone system that plays a central role in the control of sodium secretion, fluid volume, and vascular tone, thus controlling blood pressure.",

keywords = "Aldosterone, Angiotensin receptors, Biosynthesis, Hypertension, Renin-angiotensin system",

author = "Elena Kaschina and Steckelings, \{Ulrike M.\} and Thomas Unger",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-801238-3.03969-6",

language = "English",

isbn = "9780128121993",

pages = "505--510",

editor = "Ilpo Huhtaniemi",

booktitle = "Encyclopedia of Endocrine Diseases",

publisher = "Elsevier",

address = "United States",

}

TY - CHAP

T1 - Hypertension and the renin-angiotensin-aldosterone system

AU - Kaschina, Elena

AU - Steckelings, Ulrike M.

AU - Unger, Thomas

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Hypertension is defined as a systolic blood pressure > 140 mmHg or a diastolic blood pressure > 90 mmHg. Renin is a key enzyme of the renin-angiotensin-aldosterone system (RAAS), cleaving angiotensinogen to angiotensin I and, thereby, having an impact on the synthesis rate of the effector hormone of the RAAS, angiotensin II. The RAAS is a hormone system that plays a central role in the control of sodium secretion, fluid volume, and vascular tone, thus controlling blood pressure.

AB - Hypertension is defined as a systolic blood pressure > 140 mmHg or a diastolic blood pressure > 90 mmHg. Renin is a key enzyme of the renin-angiotensin-aldosterone system (RAAS), cleaving angiotensinogen to angiotensin I and, thereby, having an impact on the synthesis rate of the effector hormone of the RAAS, angiotensin II. The RAAS is a hormone system that plays a central role in the control of sodium secretion, fluid volume, and vascular tone, thus controlling blood pressure.

KW - Aldosterone

KW - Angiotensin receptors

KW - Biosynthesis

KW - Hypertension

KW - Renin-angiotensin system

U2 - 10.1016/B978-0-12-801238-3.03969-6

DO - 10.1016/B978-0-12-801238-3.03969-6

M3 - Chapter

SN - 9780128121993

SP - 505

EP - 510

BT - Encyclopedia of Endocrine Diseases

A2 - Huhtaniemi, Ilpo

PB - Elsevier

ER -

Hypertension and the renin-angiotensin-aldosterone system

Abstract

Keywords

Access to Document

Fingerprint

Cite this