Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation

Henri M. H. Spronk, Anne Margreet De Jong, Sander Verheule, Hetty C. De Boer, Alexander H. Maass, Dennis H. Lau, Michiel Rienstra, Arne van Hunnik, Marion Kuiper, Stijn Lumeij, Stef Zeemering, Dominik Linz, Pieter Willem Kamphuisen, Hugo ten Cate, Harry J. Crijns, Isabelle C. Van Gelder, Anton Jan van Zonneveld, Ulrich Schotten*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Original languageEnglish
Pages (from-to)38-50
Number of pages13
JournalEuropean Heart Journal
Volume38
Issue number1
DOIs
Publication statusPublished - 1 Jan 2017

Keywords

  • Atrial fibrillation
  • Hypercoagulability
  • Stroke
  • Protease-activated receptors
  • Direct thrombin inhibitors
  • Atrial fibrosis
  • PROTEASE-ACTIVATED RECEPTORS
  • CARDIAC FIBROBLASTS
  • ISCHEMIA/REPERFUSION INJURY
  • LUNG FIBROBLASTS
  • FACTOR XA
  • THROMBIN
  • COAGULATION
  • CONDUCTION
  • CARDIOMYOCYTES
  • PROLIFERATION

Cite this

Spronk, H. M. H., De Jong, A. M., Verheule, S., De Boer, H. C., Maass, A. H., Lau, D. H., Rienstra, M., van Hunnik, A., Kuiper, M., Lumeij, S., Zeemering, S., Linz, D., Kamphuisen, P. W., ten Cate, H., Crijns, H. J., Van Gelder, I. C., van Zonneveld, A. J., & Schotten, U. (2017). Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation. European Heart Journal, 38(1), 38-50. https://doi.org/10.1093/eurheartj/ehw119