Hybrid total-body pet scanners-current status and future perspectives

V. Nadig, K. Herrmann, F.M. Mottaghy, V. Schulz*

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

9 Citations (Web of Science)

Abstract

Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In the past years, especially PET systems have seen a trend towards an enlarged axial field of view (FOV), up to a factor of ten. Methods Conducting a thorough literature research, we summarize the status quo of contemporary total-body (TB) PET/CT scanners and give an outlook on possible future developments. Results Currently, three human TB PET/CT systems have been developed: The PennPET Explorer, the uExplorer, and the Biograph Vision Quadra realize aFOVs between 1 and 2 m and show a tremendous increase in system sensitivity related to their longer gantries. Conclusion The increased system sensitivity paves the way for short-term, low-dose, and dynamic TB imaging as well as new examination methods in almost all areas of imaging.
Original languageEnglish
Pages (from-to)445-459
Number of pages15
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Volume49
Issue number2
Early online date14 Oct 2021
DOIs
Publication statusPublished - Jan 2022

Keywords

  • PET
  • CT
  • MRI
  • Total-body
  • Sensitivity
  • Long axial FOV
  • MONOLITHIC SCINTILLATOR CRYSTALS
  • HIGH QUANTUM EFFICIENCY
  • PERFORMANCE EVALUATION
  • SILICON PHOTOMULTIPLIERS
  • PHOTO-DETECTORS
  • SYSTEM
  • PET/MRI
  • SIPM
  • ALGORITHMS
  • READOUT

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