Hybrid thoracoscopic and transvenous catheter ablation of atrial fibrillation

Sandro Gelsomino*, Henrica N. A. M. Van Breugel, Laurent Pison, Orlando Parise, Hanry J. G. M. Crijns, Francis Wellens, Jos G. Maessen, Mark La Meir

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

44 Citations (Web of Science)


The hybrid approach combines an epicardial ablation with a percutaneous endocardial ablation in a single-step or sequential procedure. This study provides an overview of the hybrid procedure for the treatment of stand-alone atrial fibrillation (AF). Papers selected for this review were identified on PubMed and the final selection included nine studies. The total number of patients was 335 (range 15-101). Mean age ranged from 55.2 to 62.9 years. The hybrid approach achieved satisfactory results, with AF-antiarrhythmic drug-free success rates higher than those in isolated procedures. In particular, the bilateral approach with a bipolar device showed a high success rate independently of the AF type and seems to be the better choice for the hybrid procedure. Despite good preliminary results, large, multicentre trials of hybrid AF ablation that target a population of patients with long-standing persistent disease are necessary to establish whether this approach may represent, in the future, a gold-standard treatment for AF.
Original languageEnglish
Pages (from-to)401-407
JournalEuropean Journal of Cardio-Thoracic Surgery
Issue number3
Publication statusPublished - Mar 2014


  • Atrial fibrillation
  • Ablation
  • Surgery

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