How to prepare a systematic review of economic evaluations for informing evidence-based healthcare decisions: data extraction, risk of bias, and transferability (part 3/3)

B. F. M. Wijnen*, G. A. P. G. Van Mastrigt, W. K. Redekop, H. J. M. Majoie, R. J. A. De Kinderen, S. M. A. A. Evers

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Introduction: This article is part of the series How to Prepare a Systematic Review (SR) of Economic Evaluations (EE) for Informing Evidence-based Healthcare Decisions in which a five-step-approach for conducting a SR of EE is proposed.Areas covered: This paper explains the data extraction process, the risk of bias assessment and the transferability of EEs by means of a narrative review and expert opinion. SRs play a critical role in determining the comparative cost-effectiveness of healthcare interventions. It is important to determine the risk of bias and the transferability of an EE.Expert commentary: Over the past decade, several criteria lists have been developed. This article aims to provide recommendations on these criteria lists based on the thoroughness of development, feasibility, overall quality, recommendations of leading organizations, and widespread use.
Original languageEnglish
Pages (from-to)723-732
JournalExpert Review of Pharmacoeconomics & Outcomes Research
Issue number6
Publication statusPublished - Dec 2016


  • Systematic reviews
  • economic evaluations
  • clinical practice guidelines
  • risk of bias
  • quality appraisal
  • data-extraction

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