How Do Dual Long-Acting Bronchodilators Prevent Exacerbations of Chronic Obstructive Pulmonary Disease?

Kai M. Beeh*, Pierre-Regis Burgel, Frits M. E. Franssen, Jose Luis Lopez-Campos, Stelios Loukides, John R. Hurst, Matjaz Flezar, Charlotte Suppli Ulrik, Fabiano Di Marco, Daiana Stolz, Arschang Valipour, Brian Casserly, Bjorn Stallberg, Konstantinos Kostikas, Jadwiga A. Wedzicha

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

45 Citations (Web of Science)
Original languageEnglish
Pages (from-to)139-149
Number of pages11
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume196
Issue number2
DOIs
Publication statusPublished - 15 Jul 2017

Keywords

  • hyperinflation
  • inflammation
  • inhaled corticosteroid
  • mucus
  • RANDOMIZED CONTROLLED-TRIALS
  • LUNG-VOLUME REDUCTION
  • COPD EXACERBATIONS
  • TIOTROPIUM BROMIDE
  • MUCUS HYPERSECRETION
  • EPITHELIAL-CELLS
  • DOUBLE-BLIND
  • SALMETEROL/FLUTICASONE PROPIONATE
  • NEUTROPHILIC INFLAMMATION
  • DYNAMIC HYPERINFLATION

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