Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology

S. Bagayoko, S.A. Leon-Icaza, M. Pinilla, A. Hessel, K. Santoni, D. Pericat, P.J. Bordignon, F. Moreau, E. Eren, A. Boyance, E. Naser, L. Lefevre, C. Berrone, N. Iakobachvili, A. Metais, Y. Rombouts, G. Lugo-Villarino, A. Coste, I. Attree, D.W. FrankH. Clevers, P.J. Peters, C. Cougoule, R. Planes*, E. Meunier*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article numbere1009927
Number of pages29
JournalPLOS PATHOGENS
Volume17
Issue number9
DOIs
Publication statusPublished - 1 Sep 2021

Keywords

  • PATATIN-LIKE PHOSPHOLIPASES
  • LIPID-PEROXIDATION
  • IMMUNE RECOGNITION
  • OXIDATIVE STRESS
  • SECRETION SYSTEM
  • CYTOTOXIN EXOU
  • A(2) ENZYMES
  • FERROPTOSIS
  • VIRULENCE
  • DEATH

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