Hospital-based cluster randomised controlled trial to assess effects of a multi-faceted programme on influenza vaccine coverage among hospital healthcare workers and nosocomial influenza in the Netherlands, 2009 to 2011

J. Riphagen-Dalhuisen; J. G. Burgerhof; G. Frijstein; A. D. van der Geest-Blankert; M. B. Danhof-Pont; H. J. de Jager; A. A. Bos; E. E. Smeets; M. J. de Vries; P. M. Gallee; E. Hak

doi:10.2807/1560-7917.ES2013.18.26.20512

Hospital-based cluster randomised controlled trial to assess effects of a multi-faceted programme on influenza vaccine coverage among hospital healthcare workers and nosocomial influenza in the Netherlands, 2009 to 2011

J. Riphagen-Dalhuisen^*, J. G. Burgerhof, G. Frijstein, A. D. van der Geest-Blankert, M. B. Danhof-Pont, H. J. de Jager, A. A. Bos, E. E. Smeets, M. J. de Vries, P. M. Gallee, E. Hak

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Web of Science)

Abstract

Nosocomial influenza is a large burden in hospitals. Despite recommendations from the World Health Organization to vaccinate healthcare workers against influenza, vaccine uptake remains low in most European countries. We performed a pragmatic cluster randomised controlled trial in order to assess the effects of implementing a multi-faceted influenza immunisation programme on vaccine coverage in hospital healthcare workers (HCWs) and on in-patient morbidity. We included hospital HCWs of three intervention and three control University Medical Centers (UMCs), and 3,367 patients. An implementation programme was offered to the intervention UMCs to assess the effects on both vaccine uptake among hospital staff and patient morbidity. In 2009/10, the coverage of seasonal, the first and second dose of pandemic influenza vaccine as well as seasonal vaccine in 2010/11 was higher in intervention UMCs than control UMCs (all p

Original language	English
Pages (from-to)	10-19
Journal	Eurosurveillance
Volume	18
Issue number	26
DOIs	https://doi.org/10.2807/1560-7917.ES2013.18.26.20512
Publication status	Published - 27 Jun 2013

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10.2807/1560-7917.ES2013.18.26.20512

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Riphagen-Dalhuisen, J., Burgerhof, J. G., Frijstein, G., van der Geest-Blankert, A. D., Danhof-Pont, M. B., de Jager, H. J., Bos, A. A., Smeets, E. E., de Vries, M. J., Gallee, P. M., & Hak, E. (2013). Hospital-based cluster randomised controlled trial to assess effects of a multi-faceted programme on influenza vaccine coverage among hospital healthcare workers and nosocomial influenza in the Netherlands, 2009 to 2011. Eurosurveillance, 18(26), 10-19. https://doi.org/10.2807/1560-7917.ES2013.18.26.20512

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abstract = "Nosocomial influenza is a large burden in hospitals. Despite recommendations from the World Health Organization to vaccinate healthcare workers against influenza, vaccine uptake remains low in most European countries. We performed a pragmatic cluster randomised controlled trial in order to assess the effects of implementing a multi-faceted influenza immunisation programme on vaccine coverage in hospital healthcare workers (HCWs) and on in-patient morbidity. We included hospital HCWs of three intervention and three control University Medical Centers (UMCs), and 3,367 patients. An implementation programme was offered to the intervention UMCs to assess the effects on both vaccine uptake among hospital staff and patient morbidity. In 2009/10, the coverage of seasonal, the first and second dose of pandemic influenza vaccine as well as seasonal vaccine in 2010/11 was higher in intervention UMCs than control UMCs (all p",

author = "J. Riphagen-Dalhuisen and Burgerhof, {J. G.} and G. Frijstein and {van der Geest-Blankert}, {A. D.} and Danhof-Pont, {M. B.} and {de Jager}, {H. J.} and Bos, {A. A.} and Smeets, {E. E.} and {de Vries}, {M. J.} and Gallee, {P. M.} and E. Hak",

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Riphagen-Dalhuisen, J, Burgerhof, JG, Frijstein, G, van der Geest-Blankert, AD, Danhof-Pont, MB, de Jager, HJ, Bos, AA, Smeets, EE, de Vries, MJ, Gallee, PM & Hak, E 2013, 'Hospital-based cluster randomised controlled trial to assess effects of a multi-faceted programme on influenza vaccine coverage among hospital healthcare workers and nosocomial influenza in the Netherlands, 2009 to 2011', Eurosurveillance, vol. 18, no. 26, pp. 10-19. https://doi.org/10.2807/1560-7917.ES2013.18.26.20512

Hospital-based cluster randomised controlled trial to assess effects of a multi-faceted programme on influenza vaccine coverage among hospital healthcare workers and nosocomial influenza in the Netherlands, 2009 to 2011. / Riphagen-Dalhuisen, J.; Burgerhof, J. G.; Frijstein, G. et al.

In: Eurosurveillance, Vol. 18, No. 26, 27.06.2013, p. 10-19.

Research output: Contribution to journal › Article › Academic › peer-review

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Riphagen-Dalhuisen J, Burgerhof JG, Frijstein G, van der Geest-Blankert AD, Danhof-Pont MB, de Jager HJ et al. Hospital-based cluster randomised controlled trial to assess effects of a multi-faceted programme on influenza vaccine coverage among hospital healthcare workers and nosocomial influenza in the Netherlands, 2009 to 2011. Eurosurveillance. 2013 Jun 27;18(26):10-19. doi: 10.2807/1560-7917.ES2013.18.26.20512