Homology and Specificity of Natural Sound-Encoding in Human and Monkey Auditory Cortex

Julia Erb, Marcelo Armendariz, Federico De Martino, Rainer Goebel, Wim Vanduffel, Elia Formisano

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Understanding homologies and differences in auditory cortical processing in human and nonhuman primates is an essential step in elucidating the neurobiology of speech and language. Using fMRI responses to natural sounds, we investigated the representation of multiple acoustic features in auditory cortex of awake macaques and humans. Comparative analyses revealed homologous large-scale topographies not only for frequency but also for temporal and spectral modulations. In both species, posterior regions preferably encoded relatively fast temporal and coarse spectral information, whereas anterior regions encoded slow temporal and fine spectral modulations. Conversely, we observed a striking interspecies difference in cortical sensitivity to temporal modulations: While decoding from macaque auditory cortex was most accurate at fast rates (> 30 Hz), humans had highest sensitivity to ~3 Hz, a relevant rate for speech analysis. These findings suggest that characteristic tuning of human auditory cortex to slow temporal modulations is unique and may have emerged as a critical step in the evolution of speech and language.
Original languageEnglish
Article numberbhy243
Pages (from-to)3636–3650
Number of pages15
JournalCerebral Cortex
Volume29
Issue number9
Early online date3 Nov 2018
DOIs
Publication statusPublished - Sep 2019

Keywords

  • AMPLITUDE-MODULATION
  • COMPLEX SOUNDS
  • DORSAL STREAM
  • FREQUENCY
  • FUNCTIONAL SPECIALIZATION
  • MODULATION TRANSFER-FUNCTIONS
  • REPRESENTATION
  • RIDGE-REGRESSION
  • TEMPORAL ENVELOPE
  • TONOTOPIC ORGANIZATION
  • functional MRI
  • primate auditory cortex
  • rhesus macaque
  • spectrotemporal modulations
  • tonotopy

Cite this

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title = "Homology and Specificity of Natural Sound-Encoding in Human and Monkey Auditory Cortex",
abstract = "Understanding homologies and differences in auditory cortical processing in human and nonhuman primates is an essential step in elucidating the neurobiology of speech and language. Using fMRI responses to natural sounds, we investigated the representation of multiple acoustic features in auditory cortex of awake macaques and humans. Comparative analyses revealed homologous large-scale topographies not only for frequency but also for temporal and spectral modulations. In both species, posterior regions preferably encoded relatively fast temporal and coarse spectral information, whereas anterior regions encoded slow temporal and fine spectral modulations. Conversely, we observed a striking interspecies difference in cortical sensitivity to temporal modulations: While decoding from macaque auditory cortex was most accurate at fast rates (> 30 Hz), humans had highest sensitivity to ~3 Hz, a relevant rate for speech analysis. These findings suggest that characteristic tuning of human auditory cortex to slow temporal modulations is unique and may have emerged as a critical step in the evolution of speech and language.",
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Homology and Specificity of Natural Sound-Encoding in Human and Monkey Auditory Cortex. / Erb, Julia; Armendariz, Marcelo; De Martino, Federico; Goebel, Rainer; Vanduffel, Wim; Formisano, Elia.

In: Cerebral Cortex, Vol. 29, No. 9, bhy243, 09.2019, p. 3636–3650.

Research output: Contribution to journalArticleAcademicpeer-review

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