Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis

Pooja R. Mandaviya, Dylan Aissi, Koen F. Dekkers, Roby Joehanes, Silva Kasela, Vinh Truong, Lisette Stolk, Diana van Heemst, M. Arfan Ikram, Jan Lindemans, P. Eline Slagboom, David-Alexandre Tregouet, Andre G. Uitterlinden, Chen Wei, Phil Wells, France Gagnon, Marleen M. J. van Greevenbroek, Bastiaan T. Heijmans, Lili Milani, Pierre-Emmanuel MorangeJoyce B. J. van Meurs, Sandra G. Heil*, BIOS Consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1403-1422
Number of pages20
JournalEpigenomics
Volume9
Issue number11
DOIs
Publication statusPublished - Nov 2017

Keywords

  • 450 k array
  • association
  • DMP
  • DMR
  • DNA methylation
  • epigenome-wide analysis
  • homocysteine
  • meta-analysis
  • RANDOMIZED CONTROLLED-TRIAL
  • ESTROGEN-RECEPTOR-ALPHA
  • SMOOTH-MUSCLE-CELLS
  • PLASMA HOMOCYSTEINE
  • S-ADENOSYLHOMOCYSTEINE
  • GENOME-WIDE
  • FOLIC-ACID
  • VASCULAR-DISEASE
  • LIM PROTEIN
  • MYOCARDIAL-INFARCTION

Cite this

Mandaviya, P. R., Aissi, D., Dekkers, K. F., Joehanes, R., Kasela, S., Vinh Truong, Stolk, L., van Heemst, D., Ikram, M. A., Lindemans, J., Slagboom, P. E., Tregouet, D-A., Uitterlinden, A. G., Wei, C., Wells, P., Gagnon, F., van Greevenbroek, M. M. J., Heijmans, B. T., Milani, L., ... BIOS Consortium (2017). Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis. Epigenomics, 9(11), 1403-1422. https://doi.org/10.2217/epi-2017-0038