Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis

Pooja R. Mandaviya, Dylan Aissi, Koen F. Dekkers, Roby Joehanes, Silva Kasela, Vinh Truong, Lisette Stolk, Diana van Heemst, M. Arfan Ikram, Jan Lindemans, P. Eline Slagboom, David-Alexandre Tregouet, Andre G. Uitterlinden, Chen Wei, Phil Wells, France Gagnon, Marleen M. J. van Greevenbroek, Bastiaan T. Heijmans, Lili Milani, Pierre-Emmanuel MorangeJoyce B. J. van Meurs, Sandra G. Heil*, BIOS Consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Web of Science)
Original languageEnglish
Pages (from-to)1403-1422
Number of pages20
JournalEpigenomics
Volume9
Issue number11
DOIs
Publication statusPublished - Nov 2017

Keywords

  • 450 k array
  • association
  • DMP
  • DMR
  • DNA methylation
  • epigenome-wide analysis
  • homocysteine
  • meta-analysis
  • RANDOMIZED CONTROLLED-TRIAL
  • ESTROGEN-RECEPTOR-ALPHA
  • SMOOTH-MUSCLE-CELLS
  • PLASMA HOMOCYSTEINE
  • S-ADENOSYLHOMOCYSTEINE
  • GENOME-WIDE
  • FOLIC-ACID
  • VASCULAR-DISEASE
  • LIM PROTEIN
  • MYOCARDIAL-INFARCTION

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