HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome

Nerea Hermida, Andreas Markl, Julien Hamelet, Tim Van Assche, Annelies Vanderper, Paul Herijgers, Marc van Bilsen, Denise Hilfiker-Kleiner, Gauthier Noppe, Christophe Beauloye, Sandrine Horman, Jean-Luc Balligand*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

56 Citations (Web of Science)
Original languageEnglish
Pages (from-to)44-54
JournalCardiovascular Research
Volume99
Issue number1
DOIs
Publication statusPublished - 1 Jul 2013

Keywords

  • Myocardial fibrosis
  • Diastolic dysfunction
  • Metabolic syndrome
  • AMPK

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