Hippocampal pattern separation of emotional information determining risk or resilience in individuals exposed to childhood trauma: Linking exposure to neurodevelopmental alterations and threat anticipation

Aleksandra Lecei; Ruud van Winkel

doi:10.1016/j.neubiorev.2019.11.010

Hippocampal pattern separation of emotional information determining risk or resilience in individuals exposed to childhood trauma: Linking exposure to neurodevelopmental alterations and threat anticipation

Aleksandra Lecei, Ruud van Winkel^*

^*Corresponding author for this work

MHeNs - Neuroscience

Research output: Contribution to journal › Review article › peer-review

Original language	English
Pages (from-to)	160-170
Number of pages	11
Journal	Neuroscience and Biobehavioral Reviews
Volume	108
DOIs	https://doi.org/10.1016/j.neubiorev.2019.11.010
Publication status	Published - Jan 2020

Keywords

Childhood trauma
Maltreatment
Adversity
Hippocampus
Amygdala
Pattern separation
Episodic memory
Emotional modulation
DG
CA3
Threat anticipation
Fear generalization
Stress
Resilience
POSTTRAUMATIC-STRESS-DISORDER
LONG-TERM POTENTIATION
PROLONGED GLUCOCORTICOID EXPOSURE
LEARNING-THEORY PERSPECTIVE
DENTATE GYRUS
PREFRONTAL CORTEX
BASOLATERAL AMYGDALA
VOLUME REDUCTION
GRANULE CELLS
FREQUENCY STIMULATION

Access to Document

10.1016/j.neubiorev.2019.11.010

Cite this

@article{b4fe32813e5d4eb7b31ec183fa62d084,

title = "Hippocampal pattern separation of emotional information determining risk or resilience in individuals exposed to childhood trauma: Linking exposure to neurodevelopmental alterations and threat anticipation",

keywords = "Childhood trauma, Maltreatment, Adversity, Hippocampus, Amygdala, Pattern separation, Episodic memory, Emotional modulation, DG, CA3, Threat anticipation, Fear generalization, Stress, Resilience, POSTTRAUMATIC-STRESS-DISORDER, LONG-TERM POTENTIATION, PROLONGED GLUCOCORTICOID EXPOSURE, LEARNING-THEORY PERSPECTIVE, DENTATE GYRUS, PREFRONTAL CORTEX, BASOLATERAL AMYGDALA, VOLUME REDUCTION, GRANULE CELLS, FREQUENCY STIMULATION",

author = "Aleksandra Lecei and {van Winkel}, Ruud",

year = "2020",

month = jan,

doi = "10.1016/j.neubiorev.2019.11.010",

language = "English",

volume = "108",

pages = "160--170",

journal = "Neuroscience and Biobehavioral Reviews",

issn = "0149-7634",

publisher = "Elsevier Science",

}

Hippocampal pattern separation of emotional information determining risk or resilience in individuals exposed to childhood trauma : Linking exposure to neurodevelopmental alterations and threat anticipation. / Lecei, Aleksandra; van Winkel, Ruud.

In: Neuroscience and Biobehavioral Reviews, Vol. 108, 01.2020, p. 160-170.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Hippocampal pattern separation of emotional information determining risk or resilience in individuals exposed to childhood trauma

T2 - Linking exposure to neurodevelopmental alterations and threat anticipation

AU - Lecei, Aleksandra

AU - van Winkel, Ruud

PY - 2020/1

Y1 - 2020/1

KW - Childhood trauma

KW - Maltreatment

KW - Adversity

KW - Hippocampus

KW - Amygdala

KW - Pattern separation

KW - Episodic memory

KW - Emotional modulation

KW - DG

KW - CA3

KW - Threat anticipation

KW - Fear generalization

KW - Stress

KW - Resilience

KW - POSTTRAUMATIC-STRESS-DISORDER

KW - LONG-TERM POTENTIATION

KW - PROLONGED GLUCOCORTICOID EXPOSURE

KW - LEARNING-THEORY PERSPECTIVE

KW - DENTATE GYRUS

KW - PREFRONTAL CORTEX

KW - BASOLATERAL AMYGDALA

KW - VOLUME REDUCTION

KW - GRANULE CELLS

KW - FREQUENCY STIMULATION

U2 - 10.1016/j.neubiorev.2019.11.010

DO - 10.1016/j.neubiorev.2019.11.010

M3 - Review article

C2 - 31743725

VL - 108

SP - 160

EP - 170

JO - Neuroscience and Biobehavioral Reviews

JF - Neuroscience and Biobehavioral Reviews

SN - 0149-7634

ER -