Hippocampal activity in working memory tasks: sparse, yet relevant

Judith C. Peters*, Joel Reithler

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review


Recent studies suggest the hippocampus is involved in working memory (WM). Slotnick (this issue) critically reviewed relevant fMRI findings and concludes WM 'does not activate the hippocampus.' We extend Slotnick's review by discussing observations from human intracranial and lesion research. These studies do suggest hippocampal contributions to WM (beyond novelty encoding), which however are difficult to capture with conventional fMRI. Still, the advent of new fMRI techniques combined with a stronger emphasis on shared hippocampal mechanisms across short- and long-term memory pave an exciting path forward.

Original languageEnglish
Pages (from-to)212-214
Number of pages3
JournalCognitive Neuroscience
Issue number3-4
Publication statusPublished - Oct 2022

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