Hinge-deleted IgG4 blocker therapy for acetylcholine receptor myasthenia gravis in rhesus monkeys

Mario Losen, Aran F. Labrijn, Vivianne H. van Kranen-Mastenbroek, Maarten L. Janmaat, Krista G. Haanstra, Frank J. Beurskens, Tom Vink, Margreet Jonker, Bert A. 't Hart, Marina Mane-Damas, Peter C. Molenaar, Pilar Martinez-Martinez, Eline van der Esch, Janine Schuurman, Marc H. de Baets, Paul W. H. I. Parren

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number992
Number of pages11
JournalScientific Reports
Volume7
DOIs
Publication statusPublished - 20 Apr 2017

Keywords

  • FAB-ARM EXCHANGE
  • MAIN IMMUNOGENIC REGION
  • FC-GAMMA-RIIA
  • 3-DIMENSIONAL STRUCTURE
  • INTERACTION STRENGTH
  • MONOCLONAL-ANTIBODY
  • NERVE-STIMULATION
  • PASSIVE TRANSFER
  • REFERENCE VALUES
  • IMMUNOGLOBULIN

Cite this

Losen, M., Labrijn, A. F., van Kranen-Mastenbroek, V. H., Janmaat, M. L., Haanstra, K. G., Beurskens, F. J., Vink, T., Jonker, M., 't Hart, B. A., Mane-Damas, M., Molenaar, P. C., Martinez-Martinez, P., van der Esch, E., Schuurman, J., de Baets, M. H., & Parren, P. W. H. I. (2017). Hinge-deleted IgG4 blocker therapy for acetylcholine receptor myasthenia gravis in rhesus monkeys. Scientific Reports, 7, [992]. https://doi.org/10.1038/s41598-017-01019-5