High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients

Karin van den Hurk; Balazs Balint; Sinead Toomey; Patrick C. O'Leary; Louise Unwin; Kieran Sheahan; Enda W. McDermott; Ian Murphy; Joost J. van den Oord; Mairin Rafferty; Dara M. FitzGerald; Julie Moran; Robert Cummins; Owen MacEneaney; Elaine W. Kay; Cathal P. O'Brien; Stephen P. Finn; Cynthia C. B. B. Heffron; Michelle Murphy; Ruben Yela; Derek G. Power; Padraic J. Regan; Clodagh M. McDermott; Allan O'Keeffe; Zsolt Orosz; Paul P. Donnellan; John P. Crown; Bryan T. Hennessy; William M. Gallagher

doi:10.1097/CMR.0000000000000149

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients

Karin van den Hurk, Balazs Balint, Sinead Toomey, Patrick C. O'Leary, Louise Unwin, Kieran Sheahan, Enda W. McDermott, Ian Murphy, Joost J. van den Oord, Mairin Rafferty, Dara M. FitzGerald, Julie Moran, Robert Cummins, Owen MacEneaney, Elaine W. Kay, Cathal P. O'Brien, Stephen P. Finn, Cynthia C. B. B. Heffron, Michelle Murphy, Ruben YelaDerek G. Power, Padraic J. Regan, Clodagh M. McDermott, Allan O'Keeffe, Zsolt Orosz, Paul P. Donnellan, John P. Crown, Bryan T. Hennessy, William M. Gallagher^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	189-199
Journal	Melanoma Research
Volume	25
Issue number	3
DOIs	https://doi.org/10.1097/CMR.0000000000000149
Publication status	Published - Jun 2015

Keywords

BRAF
genetics
genotyping
melanoma
MET
mutation profiling
PIK3R1

Access to Document

10.1097/CMR.0000000000000149

Cite this

van den Hurk, K., Balint, B., Toomey, S., O'Leary, P. C., Unwin, L., Sheahan, K., McDermott, E. W., Murphy, I., van den Oord, J. J., Rafferty, M., FitzGerald, D. M., Moran, J., Cummins, R., MacEneaney, O., Kay, E. W., O'Brien, C. P., Finn, S. P., Heffron, C. C. B. B., Murphy, M., ... Gallagher, W. M. (2015). High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients. Melanoma Research, 25(3), 189-199. https://doi.org/10.1097/CMR.0000000000000149

van den Hurk, Karin ; Balint, Balazs ; Toomey, Sinead ; O'Leary, Patrick C. ; Unwin, Louise ; Sheahan, Kieran ; McDermott, Enda W. ; Murphy, Ian ; van den Oord, Joost J. ; Rafferty, Mairin ; FitzGerald, Dara M. ; Moran, Julie ; Cummins, Robert ; MacEneaney, Owen ; Kay, Elaine W. ; O'Brien, Cathal P. ; Finn, Stephen P. ; Heffron, Cynthia C. B. B. ; Murphy, Michelle ; Yela, Ruben ; Power, Derek G. ; Regan, Padraic J. ; McDermott, Clodagh M. ; O'Keeffe, Allan ; Orosz, Zsolt ; Donnellan, Paul P. ; Crown, John P. ; Hennessy, Bryan T. ; Gallagher, William M. / High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients. In: Melanoma Research. 2015 ; Vol. 25, No. 3. pp. 189-199.

@article{8974a8f0d6fd4b46936c8c4550d67990,

title = "High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients",

keywords = "BRAF, genetics, genotyping, melanoma, MET, mutation profiling, PIK3R1",

author = "{van den Hurk}, Karin and Balazs Balint and Sinead Toomey and O'Leary, {Patrick C.} and Louise Unwin and Kieran Sheahan and McDermott, {Enda W.} and Ian Murphy and {van den Oord}, {Joost J.} and Mairin Rafferty and FitzGerald, {Dara M.} and Julie Moran and Robert Cummins and Owen MacEneaney and Kay, {Elaine W.} and O'Brien, {Cathal P.} and Finn, {Stephen P.} and Heffron, {Cynthia C. B. B.} and Michelle Murphy and Ruben Yela and Power, {Derek G.} and Regan, {Padraic J.} and McDermott, {Clodagh M.} and Allan O'Keeffe and Zsolt Orosz and Donnellan, {Paul P.} and Crown, {John P.} and Hennessy, {Bryan T.} and Gallagher, {William M.}",

year = "2015",

month = jun,

doi = "10.1097/CMR.0000000000000149",

language = "English",

volume = "25",

pages = "189--199",

journal = "Melanoma Research",

issn = "0960-8931",

publisher = "LIPPINCOTT WILLIAMS & WILKINS",

number = "3",

}

van den Hurk, K, Balint, B, Toomey, S, O'Leary, PC, Unwin, L, Sheahan, K, McDermott, EW, Murphy, I, van den Oord, JJ, Rafferty, M, FitzGerald, DM, Moran, J, Cummins, R, MacEneaney, O, Kay, EW, O'Brien, CP, Finn, SP, Heffron, CCBB, Murphy, M, Yela, R, Power, DG, Regan, PJ, McDermott, CM, O'Keeffe, A, Orosz, Z, Donnellan, PP, Crown, JP, Hennessy, BT & Gallagher, WM 2015, 'High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients', Melanoma Research, vol. 25, no. 3, pp. 189-199. https://doi.org/10.1097/CMR.0000000000000149

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients. / van den Hurk, Karin; Balint, Balazs; Toomey, Sinead; O'Leary, Patrick C.; Unwin, Louise; Sheahan, Kieran; McDermott, Enda W.; Murphy, Ian; van den Oord, Joost J.; Rafferty, Mairin; FitzGerald, Dara M.; Moran, Julie; Cummins, Robert; MacEneaney, Owen; Kay, Elaine W.; O'Brien, Cathal P.; Finn, Stephen P.; Heffron, Cynthia C. B. B.; Murphy, Michelle; Yela, Ruben; Power, Derek G.; Regan, Padraic J.; McDermott, Clodagh M.; O'Keeffe, Allan; Orosz, Zsolt; Donnellan, Paul P.; Crown, John P.; Hennessy, Bryan T.; Gallagher, William M.

In: Melanoma Research, Vol. 25, No. 3, 06.2015, p. 189-199.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients

AU - van den Hurk, Karin

AU - Balint, Balazs

AU - Toomey, Sinead

AU - O'Leary, Patrick C.

AU - Unwin, Louise

AU - Sheahan, Kieran

AU - McDermott, Enda W.

AU - Murphy, Ian

AU - van den Oord, Joost J.

AU - Rafferty, Mairin

AU - FitzGerald, Dara M.

AU - Moran, Julie

AU - Cummins, Robert

AU - MacEneaney, Owen

AU - Kay, Elaine W.

AU - O'Brien, Cathal P.

AU - Finn, Stephen P.

AU - Heffron, Cynthia C. B. B.

AU - Murphy, Michelle

AU - Yela, Ruben

AU - Power, Derek G.

AU - Regan, Padraic J.

AU - McDermott, Clodagh M.

AU - O'Keeffe, Allan

AU - Orosz, Zsolt

AU - Donnellan, Paul P.

AU - Crown, John P.

AU - Hennessy, Bryan T.

AU - Gallagher, William M.

PY - 2015/6

Y1 - 2015/6

KW - BRAF

KW - genetics

KW - genotyping

KW - melanoma

KW - MET

KW - mutation profiling

KW - PIK3R1

U2 - 10.1097/CMR.0000000000000149

DO - 10.1097/CMR.0000000000000149

M3 - Article

C2 - 25746038

VL - 25

SP - 189

EP - 199

JO - Melanoma Research

JF - Melanoma Research

SN - 0960-8931

IS - 3

ER -