Hepatic PPAR alpha is critical in the metabolic adaptation to sepsis

Rejane Paumelle, Joel T. Haas, Nathalie Hennuyer, Eric Bauge, Yann Deleye, Dieter Mesotten, Lies Langouche, Jonathan Vanhoutte, Celine Cudejko, Kristiaan Wouters, Sarah Anissa Hannou, Vanessa Legry, Steve Lancel, Fanny Lalloyer, Arnaud Polizzi, Sarra Smati, Pierre Gourdy, Emmanuelle Vallez, Emmanuel Bouchaert, Bruno DerudasHelene Dehondt, Celine Gheeraert, Sebastien Fleury, Anne Tailleux, Alexandra Montagner, Walter Wahli, Greet Van den Berghe, Herve Guillou, David Dombrowicz, Bart Staels*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)963-973
Number of pages11
JournalJournal of Hepatology
Volume70
Issue number5
DOIs
Publication statusPublished - May 2019

Keywords

  • Nuclear receptors
  • Sepsis
  • Metabolism
  • Hepatocytes
  • Inflammation
  • PROLIFERATOR-ACTIVATED RECEPTORS
  • INTENSIVE INSULIN THERAPY
  • FATTY-ACID OXIDATION
  • GENE-EXPRESSION
  • PROTECTS
  • INFLAMMATION
  • LIVER
  • TOLERANCE
  • BACTERIAL
  • SURVIVAL

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