Abstract
Objective: To investigate the influence of hemodilution and arterial pCO(2) on cerebral autoregulation and cerebral vascular CO2 reactivity. Design: Prospective interventional study. Setting: University hospital-based single-center study. Participants: Forty adult patients undergoing elective cardiac surgery using normothermic cardiopulmonary bypass. Interventions: Blood pressure variations induced by 6/minute metronome-triggered breathing (baseline) and cyclic 6/min changes of indexed pump flow at 3 levels of arterial pCO(2). Measurements and Main Results: Based on median hematocrit on bypass, patients were assigned to either a group of a hematocrit >= 28% or = 28% and
Original language | English |
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Pages (from-to) | 1194-1199 |
Journal | Journal of Cardiothoracic and Vascular Anesthesia |
Volume | 29 |
Issue number | 5 |
DOIs | |
Publication status | Published - Oct 2015 |
Keywords
- cardiopulmonary bypass
- cerebral autoregulation
- cerebral carbon dioxide reactivity
- hemodilution