Health-Related Quality of Life in Patients With Atrial Fibrillation Treated With Rhythm Control Versus Rate Control Insights From a Prospective International Registry (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation: RECORD-AF)

Andrew C. T. Ha; Guenter Breithardt; A. John Camm; Harry J. Crijns; Garrett M. Fitzmaurice; Peter R. Kowey; Jean-Yves Le Heuzey; Lisa Naditch-Brule; Eric N. Prystowsky; Peter J. Schwartz; Christian Torp-Pedersen; William S. Weintraub; Paul Dorian

doi:10.1161/HCQ.0000000000000011

Health-Related Quality of Life in Patients With Atrial Fibrillation Treated With Rhythm Control Versus Rate Control Insights From a Prospective International Registry (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation: RECORD-AF)

Andrew C. T. Ha^*, Guenter Breithardt, A. John Camm, Harry J. Crijns, Garrett M. Fitzmaurice, Peter R. Kowey, Jean-Yves Le Heuzey, Lisa Naditch-Brule, Eric N. Prystowsky, Peter J. Schwartz, Christian Torp-Pedersen, William S. Weintraub, Paul Dorian

^*Corresponding author for this work

Cardiologie

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background-Improving health-related quality of life (HRQoL) is an important treatment goal in the management of patients with atrial fibrillation (AF). Uncertainty exists as to whether patients' HRQoL differ when treated with medical rhythm control or rate control. We compared HRQoL between patients treated with rhythm control or rate control in a large observational registry of patients with recent-onset AF. Methods and Results-In the Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation (RECORD-AF), 2439 patients with recent onset (= 3 points. The primary analysis was based on a propensity score-adjusted longitudinal regression analysis which compared the change in AF symptom severity scores between the 2 groups. Over an average follow-up of 1 year, the AF symptom severity scores improved in both groups (rhythm control: -2.82 point [95% confidence interval, -3.22 to -2.41]; rate control: -2.11 point [95% confidence interval, -2.54 to -1.67]; P

Original language	English
Pages (from-to)	896-904
Journal	Circulation : Cardiovascular Quality and Outcomes
Volume	7
Issue number	6
DOIs	https://doi.org/10.1161/HCQ.0000000000000011
Publication status	Published - Nov 2014

Keywords

atrial fibrillation
quality of life

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Ha, A. C. T., Breithardt, G., Camm, A. J., Crijns, H. J., Fitzmaurice, G. M., Kowey, P. R., Le Heuzey, J.-Y., Naditch-Brule, L., Prystowsky, E. N., Schwartz, P. J., Torp-Pedersen, C., Weintraub, W. S., & Dorian, P. (2014). Health-Related Quality of Life in Patients With Atrial Fibrillation Treated With Rhythm Control Versus Rate Control Insights From a Prospective International Registry (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation: RECORD-AF). Circulation : Cardiovascular Quality and Outcomes, 7(6), 896-904. https://doi.org/10.1161/HCQ.0000000000000011

Ha, Andrew C. T. ; Breithardt, Guenter ; Camm, A. John et al. / Health-Related Quality of Life in Patients With Atrial Fibrillation Treated With Rhythm Control Versus Rate Control Insights From a Prospective International Registry (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation: RECORD-AF). In: Circulation : Cardiovascular Quality and Outcomes. 2014 ; Vol. 7, No. 6. pp. 896-904.

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abstract = "Background-Improving health-related quality of life (HRQoL) is an important treatment goal in the management of patients with atrial fibrillation (AF). Uncertainty exists as to whether patients' HRQoL differ when treated with medical rhythm control or rate control. We compared HRQoL between patients treated with rhythm control or rate control in a large observational registry of patients with recent-onset AF. Methods and Results-In the Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation (RECORD-AF), 2439 patients with recent onset (= 3 points. The primary analysis was based on a propensity score-adjusted longitudinal regression analysis which compared the change in AF symptom severity scores between the 2 groups. Over an average follow-up of 1 year, the AF symptom severity scores improved in both groups (rhythm control: -2.82 point [95% confidence interval, -3.22 to -2.41]; rate control: -2.11 point [95% confidence interval, -2.54 to -1.67]; P",

keywords = "atrial fibrillation, quality of life",

author = "Ha, {Andrew C. T.} and Guenter Breithardt and Camm, {A. John} and Crijns, {Harry J.} and Fitzmaurice, {Garrett M.} and Kowey, {Peter R.} and {Le Heuzey}, Jean-Yves and Lisa Naditch-Brule and Prystowsky, {Eric N.} and Schwartz, {Peter J.} and Christian Torp-Pedersen and Weintraub, {William S.} and Paul Dorian",

year = "2014",

month = nov,

doi = "10.1161/HCQ.0000000000000011",

language = "English",

volume = "7",

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journal = "Circulation : Cardiovascular Quality and Outcomes",

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Ha, ACT, Breithardt, G, Camm, AJ, Crijns, HJ, Fitzmaurice, GM, Kowey, PR, Le Heuzey, J-Y, Naditch-Brule, L, Prystowsky, EN, Schwartz, PJ, Torp-Pedersen, C, Weintraub, WS & Dorian, P 2014, 'Health-Related Quality of Life in Patients With Atrial Fibrillation Treated With Rhythm Control Versus Rate Control Insights From a Prospective International Registry (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation: RECORD-AF)', Circulation : Cardiovascular Quality and Outcomes, vol. 7, no. 6, pp. 896-904. https://doi.org/10.1161/HCQ.0000000000000011

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Health-Related Quality of Life in Patients With Atrial Fibrillation Treated With Rhythm Control Versus Rate Control Insights From a Prospective International Registry (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation: RECORD-AF)

AU - Ha, Andrew C. T.

AU - Breithardt, Guenter

AU - Camm, A. John

AU - Crijns, Harry J.

AU - Fitzmaurice, Garrett M.

AU - Kowey, Peter R.

AU - Le Heuzey, Jean-Yves

AU - Naditch-Brule, Lisa

AU - Prystowsky, Eric N.

AU - Schwartz, Peter J.

AU - Torp-Pedersen, Christian

AU - Weintraub, William S.

AU - Dorian, Paul

PY - 2014/11

Y1 - 2014/11

N2 - Background-Improving health-related quality of life (HRQoL) is an important treatment goal in the management of patients with atrial fibrillation (AF). Uncertainty exists as to whether patients' HRQoL differ when treated with medical rhythm control or rate control. We compared HRQoL between patients treated with rhythm control or rate control in a large observational registry of patients with recent-onset AF. Methods and Results-In the Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation (RECORD-AF), 2439 patients with recent onset (= 3 points. The primary analysis was based on a propensity score-adjusted longitudinal regression analysis which compared the change in AF symptom severity scores between the 2 groups. Over an average follow-up of 1 year, the AF symptom severity scores improved in both groups (rhythm control: -2.82 point [95% confidence interval, -3.22 to -2.41]; rate control: -2.11 point [95% confidence interval, -2.54 to -1.67]; P

AB - Background-Improving health-related quality of life (HRQoL) is an important treatment goal in the management of patients with atrial fibrillation (AF). Uncertainty exists as to whether patients' HRQoL differ when treated with medical rhythm control or rate control. We compared HRQoL between patients treated with rhythm control or rate control in a large observational registry of patients with recent-onset AF. Methods and Results-In the Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation (RECORD-AF), 2439 patients with recent onset (= 3 points. The primary analysis was based on a propensity score-adjusted longitudinal regression analysis which compared the change in AF symptom severity scores between the 2 groups. Over an average follow-up of 1 year, the AF symptom severity scores improved in both groups (rhythm control: -2.82 point [95% confidence interval, -3.22 to -2.41]; rate control: -2.11 point [95% confidence interval, -2.54 to -1.67]; P

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DO - 10.1161/HCQ.0000000000000011

M3 - Article

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SN - 1941-7705

VL - 7

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JO - Circulation : Cardiovascular Quality and Outcomes

JF - Circulation : Cardiovascular Quality and Outcomes

IS - 6

ER -

Ha ACT, Breithardt G, Camm AJ, Crijns HJ, Fitzmaurice GM, Kowey PR et al. Health-Related Quality of Life in Patients With Atrial Fibrillation Treated With Rhythm Control Versus Rate Control Insights From a Prospective International Registry (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation: RECORD-AF). Circulation : Cardiovascular Quality and Outcomes. 2014 Nov;7(6):896-904. doi: 10.1161/HCQ.0000000000000011