(Health-Related) Quality of Life as an Outcome in Studies of Axial Spondyloarthritis

Uta Kiltz; David Kiefer; Annelies Boonen

doi:10.1016/j.rdc.2020.01.017

(Health-Related) Quality of Life as an Outcome in Studies of Axial Spondyloarthritis

Uta Kiltz^*, David Kiefer, Annelies Boonen

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

The most prevalent health concerns in patients with axial spondyloarthritis (axSpA) include spinal stiffness, spinal pain, mobility limitations, fatigue, and disturbed sleep. Many patients experience impairments related to extraspinal disease, extra-articular disease, or drug side effects. To capture overall life impact, self-reported measurement instruments assessing health-related quality of life (HRQoL) have been developed. This article summarizes the literature on relevant concepts and frameworks when measuring overall health or HRQoL, available measures assessing this outcome in axSpA, the hierarchical relations between overall health/ HRQoL and specific axSpA impairments, and the role of context when interpreting interventions for overall health or HRQoL outcomes.

Original language	English
Pages (from-to)	379-393
Number of pages	15
Journal	Rheumatic Disease Clinics of North America
Volume	46
Issue number	2
DOIs	https://doi.org/10.1016/j.rdc.2020.01.017
Publication status	Published - May 2020

Keywords

Axial spondyloarthritis
Health-related quality of life
Functioning and health
Contextual factors
Life satisfaction
ANKYLOSING-SPONDYLITIS
RHEUMATOID-ARTHRITIS
QUESTIONNAIRE
RELIABILITY
VALIDITY
UTILITY
INDEX
IMPROVEMENT
DISABILITY
EUROQOL

Access to Document

10.1016/j.rdc.2020.01.017

Cite this

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title = "(Health-Related) Quality of Life as an Outcome in Studies of Axial Spondyloarthritis",

abstract = "The most prevalent health concerns in patients with axial spondyloarthritis (axSpA) include spinal stiffness, spinal pain, mobility limitations, fatigue, and disturbed sleep. Many patients experience impairments related to extraspinal disease, extra-articular disease, or drug side effects. To capture overall life impact, self-reported measurement instruments assessing health-related quality of life (HRQoL) have been developed. This article summarizes the literature on relevant concepts and frameworks when measuring overall health or HRQoL, available measures assessing this outcome in axSpA, the hierarchical relations between overall health/ HRQoL and specific axSpA impairments, and the role of context when interpreting interventions for overall health or HRQoL outcomes.",

keywords = "Axial spondyloarthritis, Health-related quality of life, Functioning and health, Contextual factors, Life satisfaction, ANKYLOSING-SPONDYLITIS, RHEUMATOID-ARTHRITIS, QUESTIONNAIRE, RELIABILITY, VALIDITY, UTILITY, INDEX, IMPROVEMENT, DISABILITY, EUROQOL",

author = "Uta Kiltz and David Kiefer and Annelies Boonen",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = may,

doi = "10.1016/j.rdc.2020.01.017",

language = "English",

volume = "46",

pages = "379--393",

journal = "Rheumatic Disease Clinics of North America",

issn = "0889-857X",

publisher = "W.B. Saunders Ltd",

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AU - Kiltz, Uta

AU - Kiefer, David

AU - Boonen, Annelies

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Y1 - 2020/5

N2 - The most prevalent health concerns in patients with axial spondyloarthritis (axSpA) include spinal stiffness, spinal pain, mobility limitations, fatigue, and disturbed sleep. Many patients experience impairments related to extraspinal disease, extra-articular disease, or drug side effects. To capture overall life impact, self-reported measurement instruments assessing health-related quality of life (HRQoL) have been developed. This article summarizes the literature on relevant concepts and frameworks when measuring overall health or HRQoL, available measures assessing this outcome in axSpA, the hierarchical relations between overall health/ HRQoL and specific axSpA impairments, and the role of context when interpreting interventions for overall health or HRQoL outcomes.

AB - The most prevalent health concerns in patients with axial spondyloarthritis (axSpA) include spinal stiffness, spinal pain, mobility limitations, fatigue, and disturbed sleep. Many patients experience impairments related to extraspinal disease, extra-articular disease, or drug side effects. To capture overall life impact, self-reported measurement instruments assessing health-related quality of life (HRQoL) have been developed. This article summarizes the literature on relevant concepts and frameworks when measuring overall health or HRQoL, available measures assessing this outcome in axSpA, the hierarchical relations between overall health/ HRQoL and specific axSpA impairments, and the role of context when interpreting interventions for overall health or HRQoL outcomes.

KW - Axial spondyloarthritis

KW - Health-related quality of life

KW - Functioning and health

KW - Contextual factors

KW - Life satisfaction

KW - ANKYLOSING-SPONDYLITIS

KW - RHEUMATOID-ARTHRITIS

KW - QUESTIONNAIRE

KW - RELIABILITY

KW - VALIDITY

KW - UTILITY

KW - INDEX

KW - IMPROVEMENT

KW - DISABILITY

KW - EUROQOL

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DO - 10.1016/j.rdc.2020.01.017

M3 - (Systematic) Review article

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JO - Rheumatic Disease Clinics of North America

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