Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum

Helen E Collins; Barbara T Alexander; Alison S Care; Margie H Davenport; Sandra T Davidge; Mansoureh Eghbali; Dino A Giussani; Martijn F Hoes; Colleen G Julian; Holly A LaVoie; I Mark Olfert; Susan E Ozanne; Egle Bytautiene Prewit; Junie P Warrington; Lubo Zhang; Styliani Goulopoulou

doi:10.1152/ajpheart.00055.2024

Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum

Helen E Collins^*, Barbara T Alexander, Alison S Care, Margie H Davenport, Sandra T Davidge, Mansoureh Eghbali, Dino A Giussani, Martijn F Hoes, Colleen G Julian, Holly A LaVoie, I Mark Olfert, Susan E Ozanne, Egle Bytautiene Prewit, Junie P Warrington, Lubo Zhang, Styliani Goulopoulou^*

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Maternal mortality rates are at an all-time high across the world and are set to increase in subsequent years. Cardiovascular disease is the leading cause of death during pregnancy and postpartum, especially in the United States. Therefore, understanding the physiological changes in the cardiovascular system during normal pregnancy is necessary to understand disease-related pathology. Significant systemic and cardiovascular physiological changes occur during pregnancy that are essential for supporting the maternal-fetal dyad. The physiological impact of pregnancy on the cardiovascular system has been examined in both experimental animal models and in humans. However, there is a continued need in this field of study to provide increased rigor and reproducibility. Therefore, these guidelines aim to provide information regarding best practices and recommendations to accurately and rigorously measure cardiovascular physiology during normal and cardiovascular disease-complicated pregnancies in human and animal models.

Original language	English
Pages (from-to)	H191-H220
Journal	American Journal of Physiology-heart and Circulatory Physiology
Volume	327
Issue number	1
Early online date	17 May 2024
DOIs	https://doi.org/10.1152/ajpheart.00055.2024
Publication status	Published - 1 Jul 2024

Keywords

Normal pregnancy
animal models
cardiac physiology
hypertensive disorders of pregnancy
vascular function

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10.1152/ajpheart.00055.2024

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Collins, H. E., Alexander, B. T., Care, A. S., Davenport, M. H., Davidge, S. T., Eghbali, M., Giussani, D. A., Hoes, M. F., Julian, C. G., LaVoie, H. A., Olfert, I. M., Ozanne, S. E., Bytautiene Prewit, E., Warrington, J. P., Zhang, L., & Goulopoulou, S. (2024). Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum. American Journal of Physiology-heart and Circulatory Physiology, 327(1), H191-H220. https://doi.org/10.1152/ajpheart.00055.2024

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title = "Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum",

abstract = "Maternal mortality rates are at an all-time high across the world and are set to increase in subsequent years. Cardiovascular disease is the leading cause of death during pregnancy and postpartum, especially in the United States. Therefore, understanding the physiological changes in the cardiovascular system during normal pregnancy is necessary to understand disease-related pathology. Significant systemic and cardiovascular physiological changes occur during pregnancy that are essential for supporting the maternal-fetal dyad. The physiological impact of pregnancy on the cardiovascular system has been examined in both experimental animal models and in humans. However, there is a continued need in this field of study to provide increased rigor and reproducibility. Therefore, these guidelines aim to provide information regarding best practices and recommendations to accurately and rigorously measure cardiovascular physiology during normal and cardiovascular disease-complicated pregnancies in human and animal models.",

keywords = "Normal pregnancy, animal models, cardiac physiology, hypertensive disorders of pregnancy, vascular function",

author = "Collins, {Helen E} and Alexander, {Barbara T} and Care, {Alison S} and Davenport, {Margie H} and Davidge, {Sandra T} and Mansoureh Eghbali and Giussani, {Dino A} and Hoes, {Martijn F} and Julian, {Colleen G} and LaVoie, {Holly A} and Olfert, {I Mark} and Ozanne, {Susan E} and {Bytautiene Prewit}, Egle and Warrington, {Junie P} and Lubo Zhang and Styliani Goulopoulou",

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doi = "10.1152/ajpheart.00055.2024",

language = "English",

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Collins, HE, Alexander, BT, Care, AS, Davenport, MH, Davidge, ST, Eghbali, M, Giussani, DA, Hoes, MF, Julian, CG, LaVoie, HA, Olfert, IM, Ozanne, SE, Bytautiene Prewit, E, Warrington, JP, Zhang, L & Goulopoulou, S 2024, 'Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum', American Journal of Physiology-heart and Circulatory Physiology, vol. 327, no. 1, pp. H191-H220. https://doi.org/10.1152/ajpheart.00055.2024

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T1 - Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum

AU - Collins, Helen E

AU - Alexander, Barbara T

AU - Care, Alison S

AU - Davenport, Margie H

AU - Davidge, Sandra T

AU - Eghbali, Mansoureh

AU - Giussani, Dino A

AU - Hoes, Martijn F

AU - Julian, Colleen G

AU - LaVoie, Holly A

AU - Olfert, I Mark

AU - Ozanne, Susan E

AU - Bytautiene Prewit, Egle

AU - Warrington, Junie P

AU - Zhang, Lubo

AU - Goulopoulou, Styliani

PY - 2024/7/1

Y1 - 2024/7/1

N2 - Maternal mortality rates are at an all-time high across the world and are set to increase in subsequent years. Cardiovascular disease is the leading cause of death during pregnancy and postpartum, especially in the United States. Therefore, understanding the physiological changes in the cardiovascular system during normal pregnancy is necessary to understand disease-related pathology. Significant systemic and cardiovascular physiological changes occur during pregnancy that are essential for supporting the maternal-fetal dyad. The physiological impact of pregnancy on the cardiovascular system has been examined in both experimental animal models and in humans. However, there is a continued need in this field of study to provide increased rigor and reproducibility. Therefore, these guidelines aim to provide information regarding best practices and recommendations to accurately and rigorously measure cardiovascular physiology during normal and cardiovascular disease-complicated pregnancies in human and animal models.

AB - Maternal mortality rates are at an all-time high across the world and are set to increase in subsequent years. Cardiovascular disease is the leading cause of death during pregnancy and postpartum, especially in the United States. Therefore, understanding the physiological changes in the cardiovascular system during normal pregnancy is necessary to understand disease-related pathology. Significant systemic and cardiovascular physiological changes occur during pregnancy that are essential for supporting the maternal-fetal dyad. The physiological impact of pregnancy on the cardiovascular system has been examined in both experimental animal models and in humans. However, there is a continued need in this field of study to provide increased rigor and reproducibility. Therefore, these guidelines aim to provide information regarding best practices and recommendations to accurately and rigorously measure cardiovascular physiology during normal and cardiovascular disease-complicated pregnancies in human and animal models.

KW - Normal pregnancy

KW - animal models

KW - cardiac physiology

KW - hypertensive disorders of pregnancy

KW - vascular function

U2 - 10.1152/ajpheart.00055.2024

DO - 10.1152/ajpheart.00055.2024

M3 - (Systematic) Review article

SN - 0363-6135

VL - 327

SP - H191-H220

JO - American Journal of Physiology-heart and Circulatory Physiology

JF - American Journal of Physiology-heart and Circulatory Physiology

IS - 1

ER -

Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum

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Keywords

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