Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes

Olaf Brouwers*, Petra M. G. Niessen, Toshio Miyata, Jakob A. Ostergaard, Allan Flyvbjerg, Carine J. Peutz-Kootstra, Jonas Sieber, Peter H. Mundel, Michael Brownlee, Ben J. A. Janssen, Jo G. R. De Mey, Coen D. A. Stehouwer, Casper G. Schalkwijk

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

94 Citations (Web of Science)
Original languageEnglish
Pages (from-to)224-235
Issue number1
Publication statusPublished - Jan 2014


  • Endothelial dysfunction
  • Glycation
  • Glyoxalase-1
  • Methylglyoxal
  • Renal impairment

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